Q8VY57 · ARL8A_ARATH
- ProteinADP-ribosylation factor-like protein 8a
- GeneARL8A
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids184 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
May play a role in lysosome motility. May play a role in chromosome segregation.
(Microbial infection) Component of tomato mosaic virus (ToMV) RNA replication complexes. Required for tobamovirus multiplication, especially for efficient negative-strand RNA synthesis and viral RNA capping.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | Golgi apparatus | |
Cellular Component | late endosome membrane | |
Cellular Component | lysosomal membrane | |
Cellular Component | nucleus | |
Cellular Component | plant-type vacuole | |
Cellular Component | plasma membrane | |
Cellular Component | plasmodesma | |
Cellular Component | spindle | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Biological Process | cell division | |
Biological Process | chromosome segregation | |
Biological Process | defense response to virus | |
Biological Process | protein transport |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameADP-ribosylation factor-like protein 8a
- Short namesAtARL8a
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ8VY57
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Note: Localizes with microtubules at the spindle mid-zone during mitosis.
Features
Showing features for intramembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Intramembrane | 1-18 | Note=Mediates targeting to membranes | ||||
Sequence: MGLLEAFLNWLRSLFFKQ |
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
In double and triple mutants arl8a-1 arl8b-1 and arl8a-1 arl8b-1 arl8c-1, impaired multiplication of tomato mosaic virus (ToMV) associated with reduced production of negative-strand RNA.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 6 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000438003 | 1-184 | ADP-ribosylation factor-like protein 8a | |||
Sequence: MGLLEAFLNWLRSLFFKQEMELSLIGLQNAGKTSLVNVVATGGYSEDMIPTVGFNMRKVTKGNVTIKLWDLGGQPRFRSMWERYCRAVSAIVYVVDAADPDNLSVSKSELHDLLSKTSLNGIPLLVLGNKIDKPGALSKEALTDEMGLTSLTDREVCCFMISCKNSTNIDQVIDWLVKHSKSKN |
Proteomic databases
Expression
Gene expression databases
Interaction
Structure
Sequence
- Sequence statusComplete
- Length184
- Mass (Da)20,404
- Last updated2002-03-01 v1
- ChecksumF0492E876261BEF1
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1I9LR83 | A0A1I9LR83_ARATH | ARLA1C | 165 |
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL132965 EMBL· GenBank· DDBJ | CAB66925.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002686 EMBL· GenBank· DDBJ | AEE78600.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY072429 EMBL· GenBank· DDBJ | AAL62421.1 EMBL· GenBank· DDBJ | mRNA | ||
AY114718 EMBL· GenBank· DDBJ | AAM48037.1 EMBL· GenBank· DDBJ | mRNA |