Q8UIL2 · GUAA_AGRFC
- ProteinGMP synthase [glutamine-hydrolyzing]
- GeneguaA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids525 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the synthesis of GMP from XMP.
Catalytic activity
- XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H+
Pathway
Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 86 | Nucleophile | |||
Active site | 176 | ||||
Active site | 178 | ||||
Binding site | 230-236 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | GMP synthase activity | |
Biological Process | glutamine metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameGMP synthase [glutamine-hydrolyzing]
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Rhizobium/Agrobacterium group > Agrobacterium > Agrobacterium tumefaciens complex
Accessions
- Primary accessionQ8UIL2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000140086 | 1-525 | GMP synthase [glutamine-hydrolyzing] | ||
Interaction
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length525
- Mass (Da)57,521
- Last updated2002-06-01 v1
- Checksum581CD3C3B1F64F34
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE007869 EMBL· GenBank· DDBJ | AAK86096.1 EMBL· GenBank· DDBJ | Genomic DNA |