Q8UHR0 · RLME_AGRFC
- ProteinRibosomal RNA large subunit methyltransferase E
- GenerlmE
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids246 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
Catalytic activity
- uridine2552 in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methyluridine2552 in 23S rRNA + S-adenosyl-L-homocysteine + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 81 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 83 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 104 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 120 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 144 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Active site | 184 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | rRNA (uridine-2'-O-)-methyltransferase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibosomal RNA large subunit methyltransferase E
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Rhizobium/Agrobacterium group > Agrobacterium > Agrobacterium tumefaciens complex
Accessions
- Primary accessionQ8UHR0
- Secondary accessions
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000155464 | 1-246 | Ribosomal RNA large subunit methyltransferase E | ||
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length246
- Mass (Da)27,203
- Last updated2004-07-05 v2
- Checksum06DB8703C1743466
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE007869 EMBL· GenBank· DDBJ | AAK86428.2 EMBL· GenBank· DDBJ | Genomic DNA |