Q8UFR5 · AROQ1_AGRFC
- Protein3-dehydroquinate dehydratase 1
- GenearoQ1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids145 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes a trans-dehydration via an enolate intermediate.
Catalytic activity
- 3-dehydroquinate = 3-dehydroshikimate + H2O
Pathway
Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.
Features
Showing features for site, active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 19 | Transition state stabilizer | ||||
Sequence: R | ||||||
Active site | 24 | Proton acceptor | ||||
Sequence: Y | ||||||
Binding site | 75 | substrate | ||||
Sequence: N | ||||||
Binding site | 81 | substrate | ||||
Sequence: H | ||||||
Binding site | 88 | substrate | ||||
Sequence: D | ||||||
Active site | 101 | Proton donor | ||||
Sequence: H | ||||||
Binding site | 102-103 | substrate | ||||
Sequence: IS | ||||||
Binding site | 112 | substrate | ||||
Sequence: R |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3-dehydroquinate dehydratase activity | |
Biological Process | amino acid biosynthetic process | |
Biological Process | aromatic amino acid family biosynthetic process | |
Biological Process | chorismate biosynthetic process | |
Biological Process | quinate catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3-dehydroquinate dehydratase 1
- EC number
- Short names3-dehydroquinase 1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Rhizobium/Agrobacterium group > Agrobacterium > Agrobacterium tumefaciens complex
Accessions
- Primary accessionQ8UFR5
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000159863 | 1-145 | 3-dehydroquinate dehydratase 1 | |||
Sequence: MSNIIIVINGPNLNMLGKREPGIYGGKTLKDIENDCVNAGADLGFSVEFRQSNHEGVLVDWLHEAGERAAGVVINPGAYSHTSIALHDAIRAISTPVVEVHISNIHAREEFRHKSMVSPAAKGMICGFGPYGYVMALHALKNITA |
Interaction
Structure
Sequence
- Sequence statusComplete
- Length145
- Mass (Da)15,603
- Last updated2002-11-15 v2
- Checksum301E15931EE6036E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE007869 EMBL· GenBank· DDBJ | AAK87123.2 EMBL· GenBank· DDBJ | Genomic DNA |