Q8U2J8 · Q8U2J8_PYRFU

Function

function

Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionadenosylcobinamide-GDP ribazoletransferase activity
Molecular Functioncobalamin 5'-phosphate synthase activity
Biological Processcobalamin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylcobinamide-GDP ribazoletransferase
  • EC number
  • Alternative names
    • Cobalamin synthase
    • Cobalamin-5'-phosphate synthase

Gene names

    • Name
      cobS
    • Ordered locus names
      PF0836

Organism names

Accessions

  • Primary accession
    Q8U2J8

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane24-44Helical
Transmembrane50-70Helical
Transmembrane91-110Helical
Transmembrane130-151Helical

Keywords

PTM/Processing

Proteomic databases

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the CobS family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    155
  • Mass (Da)
    17,511
  • Last updated
    2002-06-01 v1
  • MD5 Checksum
    4222C64F350F492B55BEA21D12E3BB96
MRNIIPFMTRVPIRGNFEKARNEIWAFPLLATLTSSLPTLILYLDLPMKNILAILSLYSIIGLLHLDGLADWADGVMAKGDRKKKIKTMKDLNTCIAGIFAVVMVLFVQIYSLNYLPFYAIFLAELNSKYAMLLALATKKPLGSGLGWYFMEKMN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE009950
EMBL· GenBank· DDBJ
AAL80960.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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