Q8U1Z6 · DIPPS_PYRFU

Function

function

Involved in biosynthesis of di-myo-inositol phosphate (DIP), a widespread organic solute in microorganisms adapted to hot environments. Catalyzes the condensation of CTP and L-myo-inositol-1-phosphate into CDP-L-myo-inositol, as well as the biosynthesis of di-myo-inositol-1,3'-phosphate-1'-phosphate (DIPP) from CDP-L-myo-inositol and L-myo-inositol-1-phosphate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site14-16CTP (UniProtKB | ChEBI)
Binding site27CTP (UniProtKB | ChEBI)
Binding site119CTP (UniProtKB | ChEBI)
Binding site119Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionmetal ion binding
Molecular Functionnucleotidyltransferase activity
Molecular Functionphosphotransferase activity, for other substituted phosphate groups
Biological Processphospholipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional IPC transferase and DIPP synthase

Including 2 domains:

  • Recommended name
    1L-myo-inositol-1-phosphate cytidylyltransferase
  • EC number
  • Short names
    IPCT
  • Recommended name
    CDP-L-myo-inositol myo-inositolphosphotransferase
  • EC number
  • Short names
    DIPP synthase
  • Alternative names
    • Di-myo-inositol-1,3'-phosphate-1'-phosphate synthase

Gene names

    • Ordered locus names
      PF1058

Organism names

Accessions

  • Primary accession
    Q8U1Z6

Proteomes

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane269-289Helical
Transmembrane341-361Helical
Transmembrane390-410Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004243321-430Bifunctional IPC transferase and DIPP synthase

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region8-230MobA-like NTP transferase
Region231-428CDP-alcohol phosphatidyltransferases

Sequence similarities

In the N-terminal section; belongs to the MobA family.
In the C-terminal section; belongs to the CDP-alcohol phosphatidyltransferase class-I family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    430
  • Mass (Da)
    48,738
  • Last updated
    2002-06-01 v1
  • Checksum
    FA48115D1633D759
MNILGGEEVKGVILAAGYGSRMGEKPKGLLKIAGREILYRTIKNLEKNGIKEFIIVTNERYLQKFEEFVKENNLQNVKLAVNRFPEKGNGYSLYVAKDFVKGKFVLVMSDHIYEEKFYELALRGEGLIVDRNPKFVDIDEATKVKIENDRVVDIGKEIPSWDGVDTGFFILDDSIFSVIEDILKEKEVVELKDVVKRARLKVSYVDGLYWMDVDTPGDLKKARKLIVYSSVKGVGDGFISRYINRKISTRISALLVDHITPNKLTIVTFLFGIFSGLMNLISVPLAAILYQISSIFDGVDGEIARARMQTSKFGGFFDSILDRYVDFTYLLTLAYVTIREPIWWVIAGIAIFSSAMVSYSTERFRGAYCADAYKVVPALRKIPGKRDERIFVTMIFALLGLIKPLFALLAAWSTLRVIITIYLVWRDVNG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE009950
EMBL· GenBank· DDBJ
AAL81182.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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