Q8U0B3 · LYSK_PYRFU

Function

function

Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Co2+ (UniProtKB | Rhea| CHEBI:48828 )

Note: Binds 2 Zn2+ or Co2+ ions per subunit.

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 5/5.
Amino-acid biosynthesis; L-arginine biosynthesis.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site66Zn2+ 1 (UniProtKB | ChEBI)
Active site68
Binding site90Zn2+ 1 (UniProtKB | ChEBI)
Binding site90Zn2+ 2 (UniProtKB | ChEBI)
Active site117Proton acceptor
Binding site118Zn2+ 2 (UniProtKB | ChEBI)
Binding site139Zn2+ 1 (UniProtKB | ChEBI)
Binding site297Zn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncobalt ion binding
Molecular Functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Molecular Functionzinc ion binding
Biological Processarginine biosynthetic process via ornithine
Biological Processlysine biosynthetic process via aminoadipic acid

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative [LysW]-lysine/[LysW]-ornithine hydrolase
  • EC number

Gene names

    • Name
      lysK
    • Ordered locus names
      PF1686

Organism names

Accessions

  • Primary accession
    Q8U0B3

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001853471-326Putative [LysW]-lysine/[LysW]-ornithine hydrolase

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the peptidase M20A family. LysK subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    326
  • Mass (Da)
    35,930
  • Last updated
    2002-06-01 v1
  • Checksum
    C42E3F2A3318BE5E
MISTEEKIEFLKRLVEIYSPTGKENGVAKFLIKSFENYGIEAYLDDVGNVIAVKKGKGPLILLAGHMDTVPGYIPVRIENGELWGRGAVDAKGPLATFFFATIESDANIIFAGLVDEEGFSKGAKNLEVPKPDYIIVGEPSGTNGVTIGYKGSLTVKFTETVEKVHGSIGVGAAEKLIEKWLTIAKYFGEGFNSLSGRIVKFVAYEREFDFFGEMIVNLRTPPGYMPPKEWDIIDFVPAYEVSRTSPLVRAFVRAIRKAGYKPKLKKKTGTADTNILGPKYGVDAIAYGPGDSKLDHTPYERIKLREYLEAIEILKNAILELSSND

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE009950
EMBL· GenBank· DDBJ
AAL81810.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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