Q8TFN0 · NDK_EMENI

Function

function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site11ATP (UniProtKB | ChEBI)
Binding site59ATP (UniProtKB | ChEBI)
Binding site87ATP (UniProtKB | ChEBI)
Binding site93ATP (UniProtKB | ChEBI)
Binding site104ATP (UniProtKB | ChEBI)
Binding site114ATP (UniProtKB | ChEBI)
Active site117Pros-phosphohistidine intermediate

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionnucleoside diphosphate kinase activity
Biological Processanisotropic cell growth
Biological ProcessCTP biosynthetic process
Biological ProcessGTP biosynthetic process
Biological Processnucleoside triphosphate biosynthetic process
Biological Processphosphorylation
Biological ProcessUTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Nucleoside diphosphate kinase
  • EC number
  • Short names
    NDP kinase
  • Alternative names
    • AnNDK (NDK)

Gene names

    • Name
      swoH
    • ORF names
      AN8216

Organism names

Accessions

  • Primary accession
    Q8TFN0
  • Secondary accessions
    • C8V781
    • Q5AU14

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001371501-153Nucleoside diphosphate kinase

Keywords

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the NDK family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    153
  • Mass (Da)
    16,908
  • Last updated
    2002-06-01 v1
  • Checksum
    213D97818653EA15
MTSEQTFIAIKPDGVQRGLVGPIISRFENRGFKLAAMKLTSPSRSLLEQHYSDLKEKPFFPGLVTYMLSGPIVAMVWEGKDVVKTGRTILGATNPLASAPGTIRGDFAIDVGRNVCHGSDSVESAKKEIGLWFTPEEIQNYKLNAFGWIYEKE

Sequence caution

The sequence EAA58872.1 differs from that shown. Reason: Erroneous gene model prediction

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY057453
EMBL· GenBank· DDBJ
AAL23684.1
EMBL· GenBank· DDBJ
Genomic DNA
AACD01000144
EMBL· GenBank· DDBJ
EAA58872.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
BN001302
EMBL· GenBank· DDBJ
CBF74127.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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