Q8T3L6 · FABD_DROME
- ProteinProbable malonyl-CoA-acyl carrier protein transacylase, mitochondrial
- Genebeg
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids379 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the ACP protein. This suggests the existence of the biosynthesis of fatty acids in mitochondria (By similarity).
Catalytic activity
- holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA
Pathway
Lipid metabolism; fatty acid biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 158 | ||||
Active site | 275 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | [acyl-carrier-protein] S-malonyltransferase activity | |
Biological Process | fatty acid biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable malonyl-CoA-acyl carrier protein transacylase, mitochondrial
- EC number
- Short namesMCT
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ8T3L6
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
Phenotypes & Variants
Disruption phenotype
Eggs have a thin shell.
PTM/Processing
Features
Showing features for transit peptide, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transit peptide | 1-23 | Mitochondrion | |||
Chain | PRO_0000000590 | 24-379 | Probable malonyl-CoA-acyl carrier protein transacylase, mitochondrial | ||
Proteomic databases
Expression
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length379
- Mass (Da)42,086
- Last updated2004-06-07 v2
- MD5 ChecksumDD20710FAA862F7429193AD404A8805C
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Sequence conflict | 61 | in Ref. 3; AAM11123 | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014296 EMBL· GenBank· DDBJ | AAF49377.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY094770 EMBL· GenBank· DDBJ | AAM11123.1 EMBL· GenBank· DDBJ | mRNA | ||
BT050494 EMBL· GenBank· DDBJ | ACJ13201.1 EMBL· GenBank· DDBJ | mRNA |