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Q8T3L6 · FABD_DROME

  • Protein
    Probable malonyl-CoA-acyl carrier protein transacylase, mitochondrial
  • Gene
    beg
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the ACP protein. This suggests the existence of the biosynthesis of fatty acids in mitochondria (By similarity).

Pathway

Lipid metabolism; fatty acid biosynthesis.

Features

Showing features for active site.

137950100150200250300350
TypeIDPosition(s)Description
Active site158
Active site275

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Function[acyl-carrier-protein] S-malonyltransferase activity
Biological Processfatty acid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable malonyl-CoA-acyl carrier protein transacylase, mitochondrial
  • EC number
  • Short names
    MCT
  • Alternative names
    • Bad egg
    • [Acyl-carrier-protein] malonyltransferase

Gene names

    • Name
      beg
    • ORF names
      CG7842

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q8T3L6
  • Secondary accessions
    • B6IDQ4
    • Q9VVD5

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Eggs have a thin shell.

PTM/Processing

Features

Showing features for transit peptide, chain.

Type
IDPosition(s)Description
Transit peptide1-23Mitochondrion
ChainPRO_000000059024-379Probable malonyl-CoA-acyl carrier protein transacylase, mitochondrial

Proteomic databases

Expression

Gene expression databases

    • FBgn0036691Expressed in embryonic/larval hemocyte (Drosophila) and 21 other cell types or tissues

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the type II malonyltransferase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    379
  • Mass (Da)
    42,086
  • Last updated
    2004-06-07 v2
  • MD5 Checksum
    DD20710FAA862F7429193AD404A8805C
MLAARRLLRSPRITGALSWSRWSSDAAKATTETSALLQNAEKRQQLLNELSEPLEQKGRPAIDPKETSVMLFPGQGTQYVGMAKDLLRFPGARRIFELANEVLKYDLLKICLEGPREKLNRTEHAQLAVMVSSLAALEQLREERPKAIETCVAAAGFSLGEITALVYADALPFDKALRLVQVRATAMQAACDQAAGAMAMTLYGPDTNLGEACARAQQWCLDKGVESPYCGIANYMYPHCKVVAGNVEALEFLEQNAKSFKIRRMKRLAVSGAFHTPLMQSAVEPFTKALKTVRLQDPVIRVYSNVDGKPYRHAKHILTQLPKQIVRPVKWEQTLHEMYERKQGVDFPRTFECGPGKGLVQVLEKVNAKAAQSSFNVIA

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict61in Ref. 3; AAM11123

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014296
EMBL· GenBank· DDBJ
AAF49377.1
EMBL· GenBank· DDBJ
Genomic DNA
AY094770
EMBL· GenBank· DDBJ
AAM11123.1
EMBL· GenBank· DDBJ
mRNA
BT050494
EMBL· GenBank· DDBJ
ACJ13201.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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