Needs and targets for the multi sex combs gene product in Drosophila melanogaster.Saget O., Forquignon F., Santamaria P., Randsholt N.B.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCGenetics 149:1823-1838 (1998)Mapped to47
Identification of genes controlling germ cell migration and embryonic gonad formation in Drosophila.Moore L.A., Broihier H.T., Van Doren M., Lunsford L.B., Lehmann R.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCDevelopment 125:667-678 (1998)Mapped to82
Differential regulation of target genes by different alleles of the segmentation gene hunchback in Drosophila.Hulskamp M., Lukowitz W., Beermann A., Glaser G., Tautz D.View abstractCategoriesPhenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCGenetics 138:125-134 (1994)Mapped to15
CRISPR/Cas9-based split homing gene drive targeting <i>doublesex</i> for population suppression of the global fruit pest <i>Drosophila suzukii</i>.Yadav A.K., Butler C., Yamamoto A., Patil A.A., Lloyd A.L., Scott M.J.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCProc Natl Acad Sci U S A 120:e2301525120-e2301525120 (2023)Mapped to7
Precise genome engineering in <i>Drosophila</i> using prime editing.Bosch J.A., Birchak G., Perrimon N.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCProc Natl Acad Sci U S A 118:e2021996118-e2021996118 (2021)Mapped to18
Small-Molecule Control of Super-Mendelian Inheritance in Gene Drives.Lopez Del Amo V., Leger B.S., Cox K.J., Gill S., Bishop A.L., Scanlon G.D., Walker J.A., Gantz V.M., Choudhary A.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCCell Rep 31:107841-107841 (2020)Mapped to10
A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment.Lopez Del Amo V., Bishop A.L., Sanchez C H.M., Bennett J.B., Feng X., Marshall J.M., Bier E., Gantz V.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCNat Commun 11:352-352 (2020)Mapped to8
Impact of Wolbachia infection on Drosophila female germline stem cells.Ote M., Yamamoto D.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCCurr Opin Insect Sci 37:8-15 (2020)Mapped to29
Transforming insect population control with precision guided sterile males with demonstration in flies.Kandul N.P., Liu J., Sanchez C H.M., Wu S.L., Marshall J.M., Akbari O.S.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCNat Commun 10:84-84 (2019)Mapped to38
Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors.Tegeder I., Thiel K., Erkek S., Johann P.D., Berlandi J., Thatikonda V., Fruhwald M.C., Kool M., Jeibmann A., Hasselblatt M.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCJ Neurooncol 141:43-55 (2019)Mapped to99+
Using a phiC31 "Disintegrase" to make new attP sites in the Drosophila genome at locations showing chromosomal position effects.Maharjan M., Maeda R.K., Karch F., Hart C.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCPLoS One 13:e0205538-e0205538 (2018)Mapped to5
A sisRNA/miRNA Axis Prevents Loss of Germline Stem Cells during Starvation in Drosophila.Osman I., Pek J.W.View abstractCategoriesFunction, Expression, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCStem Cell Reports 11:4-12 (2018)Mapped to17
Identification of target genes regulated by the Drosophila histone methyltransferase Eggless reveals a role of Decapentaplegic in apoptotic signaling.Kang I., Choi Y., Jung S., Lim J.Y., Lee D., Gupta S., Moon W., Shin C.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCSci Rep 8:7123-7123 (2018)Mapped to99+
Reducing resistance allele formation in CRISPR gene drive.Champer J., Liu J., Oh S.Y., Reeves R., Luthra A., Oakes N., Clark A.G., Messer P.W.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCProc Natl Acad Sci U S A 115:5522-5527 (2018)Mapped to7
Enhancing Nanos expression via the bacterial TomO protein is a conserved strategy used by the symbiont Wolbachia to fuel germ stem cell maintenance in infected Drosophila females.Ote M., Yamamoto D.View abstractAnnotationgerm stem cell-rescuing activity of Wolbachia TomO protein appears to be tightly coupled to the ability to enhance Nos protein expressionCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962, GeneRif: 42297PubMedEurope PMCArch Insect Biochem Physiol 98:e21471-e21471 (2018)Mapped to10
Gilgamesh is required for the maintenance of germline stem cells in Drosophila testis.Chen D., Zhu X., Zhou L., Wang J., Tao X., Wang S., Sun F., Kan X., Han Z., Gu Y.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCSci Rep 7:5737-5737 (2017)Mapped to25
INFERENCE OF SPERM COMPETITION FROM BROODS OF FIELD-CAUGHT DROSOPHILA.Harshman L.G., Clark A.G.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCEvolution 52:1334-1341 (1998)Mapped to3
DNA damage-induced Lok/CHK2 activation compromises germline stem cell self-renewal and lineage differentiation.Ma X., Han Y., Song X., Do T., Yang Z., Ni J., Xie T.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCDevelopment 143:4312-4323 (2016)Mapped to39
Maternal AP determinants in the Drosophila oocyte and embryo.Ma J., He F., Xie G., Deng W.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCWiley Interdiscip Rev Dev Biol 5:562-581 (2016)Mapped to21
Importance of gene dosage in controlling dendritic arbor formation during development.Copf T.View abstractCategoriesPhenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCEur J Neurosci 42:2234-2249 (2015)Mapped to99+
Translational control in germline stem cell development.Slaidina M., Lehmann R.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCJ Cell Biol 207:13-21 (2014)Mapped to99+
The TRIM-NHL protein Brat promotes axon maintenance by repressing src64B expression.Marchetti G., Reichardt I., Knoblich J.A., Besse F.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCJ Neurosci 34:13855-13864 (2014)Mapped to25
Performance of the Cas9 nickase system in Drosophila melanogaster.Ren X., Yang Z., Mao D., Chang Z., Qiao H.H., Wang X., Sun J., Hu Q., Cui Y.[...], Ni J.Q.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCG3 (Bethesda) 4:1955-1962 (2014)Mapped to5
Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila.Port F., Chen H.M., Lee T., Bullock S.L.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCProc Natl Acad Sci U S A 111:E2967-76 (2014)Mapped to12
Piwi is required in multiple cell types to control germline stem cell lineage development in the Drosophila ovary.Ma X., Wang S., Do T., Song X., Inaba M., Nishimoto Y., Liu L.P., Gao Y., Mao Y.[...], Xie T.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0002962PubMedEurope PMCPLoS One 9:e90267-e90267 (2014)Mapped to23