Q8SXT8 · Q8SXT8_DROME
- ProteinRE22690p
- GeneSNF4Agamma
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids906 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleotide-activated protein kinase complex | |
Cellular Component | nucleus | |
Molecular Function | AMP binding | |
Molecular Function | kinase activity | |
Molecular Function | protein kinase binding | |
Molecular Function | protein kinase regulator activity | |
Biological Process | autophagy | |
Biological Process | behavioral response to starvation | |
Biological Process | cellular response to starvation | |
Biological Process | cholesterol homeostasis | |
Biological Process | fatty acid biosynthetic process | |
Biological Process | lipid metabolic process | |
Biological Process | positive regulation of cell cycle | |
Biological Process | sequestering of triglyceride |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ8SXT8
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Expression
Gene expression databases
Interaction
Subunit
AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 31-66 | Polar residues | ||||
Sequence: YGSSADASSQGSRLYSVDSSSSSSSNSNNSGGGGSG | ||||||
Region | 31-175 | Disordered | ||||
Sequence: YGSSADASSQGSRLYSVDSSSSSSSNSNNSGGGGSGTAGVENLGGVTGSAYAQWQSDRHSLPQAVPDAPRSLANHHYRNSPTHQAHYQQPTSGSLKRTPSSKRSFLERSHSPAIYGSMRRSAGPDFGSPPPTAPVGGGGYFPHDL | ||||||
Compositional bias | 105-130 | Polar residues | ||||
Sequence: HHYRNSPTHQAHYQQPTSGSLKRTPS | ||||||
Region | 218-293 | Disordered | ||||
Sequence: DDYTLPGDASRQSMNSTDSGVSSGPFNRQRFDNSSFAKSLSIDEQDPQHSPHKEGHSKHGKHHHHHSHHHHSIHEL | ||||||
Compositional bias | 222-261 | Polar residues | ||||
Sequence: LPGDASRQSMNSTDSGVSSGPFNRQRFDNSSFAKSLSIDE | ||||||
Compositional bias | 271-293 | Basic residues | ||||
Sequence: EGHSKHGKHHHHHSHHHHSIHEL | ||||||
Domain | 444-506 | CBS | ||||
Sequence: PTSAKLVVFDTQLLVKKAFYALVYNGVRAAPLWDSEKQQFVGMLTITDFIKILQMYYKSPNAS | ||||||
Domain | 523-583 | CBS | ||||
Sequence: HNQVMPLVSIGPDASLYDAIKILIHSRIHRLPVIDPATGNVLYILTHKRILRFLFLYINEL | ||||||
Domain | 598-658 | CBS | ||||
Sequence: IGTYNNIETADETTSIITALKKFVERRVSALPLVDSDGRLVDIYAKFDVINLAAEKTYNDL | ||||||
Domain | 669-729 | CBS | ||||
Sequence: RNEWFEGVQKCNLDESLYTIMERIVRAEVHRLVVVDENRKVIGIISLSDILLYLVLRPSGE | ||||||
Region | 757-888 | Disordered | ||||
Sequence: TAAAATTTTPPRSPSAGSGNRSLIEDIPEEETAPARSDDADSDNNKSASEDKANNNQHDQTTTAATANGDSNNSPVEVSFADEAQEEEAADQVERSNCDDDDQPALAEIERKNASMDDDEDDGMSSAVSAAS | ||||||
Compositional bias | 758-776 | Polar residues | ||||
Sequence: AAAATTTTPPRSPSAGSGN | ||||||
Compositional bias | 780-804 | Basic and acidic residues | ||||
Sequence: IEDIPEEETAPARSDDADSDNNKSA | ||||||
Compositional bias | 805-835 | Polar residues | ||||
Sequence: SEDKANNNQHDQTTTAATANGDSNNSPVEVS | ||||||
Compositional bias | 846-875 | Basic and acidic residues | ||||
Sequence: ADQVERSNCDDDDQPALAEIERKNASMDDD |
Sequence similarities
Belongs to the 5'-AMP-activated protein kinase gamma subunit family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length906
- Mass (Da)99,971
- Last updated2002-06-01 v1
- ChecksumC867D9556F42D57F
Computationally mapped potential isoform sequences
There are 5 potential isoforms mapped to this entry
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 31-66 | Polar residues | ||||
Sequence: YGSSADASSQGSRLYSVDSSSSSSSNSNNSGGGGSG | ||||||
Compositional bias | 105-130 | Polar residues | ||||
Sequence: HHYRNSPTHQAHYQQPTSGSLKRTPS | ||||||
Compositional bias | 222-261 | Polar residues | ||||
Sequence: LPGDASRQSMNSTDSGVSSGPFNRQRFDNSSFAKSLSIDE | ||||||
Compositional bias | 271-293 | Basic residues | ||||
Sequence: EGHSKHGKHHHHHSHHHHSIHEL | ||||||
Compositional bias | 758-776 | Polar residues | ||||
Sequence: AAAATTTTPPRSPSAGSGN | ||||||
Compositional bias | 780-804 | Basic and acidic residues | ||||
Sequence: IEDIPEEETAPARSDDADSDNNKSA | ||||||
Compositional bias | 805-835 | Polar residues | ||||
Sequence: SEDKANNNQHDQTTTAATANGDSNNSPVEVS | ||||||
Compositional bias | 846-875 | Basic and acidic residues | ||||
Sequence: ADQVERSNCDDDDQPALAEIERKNASMDDD |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY084138 EMBL· GenBank· DDBJ | AAL89876.1 EMBL· GenBank· DDBJ | mRNA | ||
AE014297 EMBL· GenBank· DDBJ | AAN13852.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE014297 EMBL· GenBank· DDBJ | AAN13853.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE014297 EMBL· GenBank· DDBJ | ABI31188.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE014297 EMBL· GenBank· DDBJ | ABI31189.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE014297 EMBL· GenBank· DDBJ | ACZ94965.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE014297 EMBL· GenBank· DDBJ | ACZ94966.1 EMBL· GenBank· DDBJ | Genomic DNA |