Q8SH21 · Q8SH21_9SAUR

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

136950100150200250300350
TypeIDPosition(s)Description
Binding site75Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site89Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site174Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site188Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site193a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      cytb

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Lepidosauria > Squamata > Bifurcata > Unidentata > Episquamata > Toxicofera > Serpentes > Colubroidea > Colubridae > Natricinae > Psammodynastes

Accessions

  • Primary accession
    Q8SH21

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane22-49Helical
Transmembrane70-91Helical
Transmembrane103-125Helical
Transmembrane132-158Helical
Transmembrane170-192Helical
Transmembrane222-242Helical
Transmembrane316-332Helical
Transmembrane338-363Helical

Keywords

Interaction

Subunit

The cytochrome bc1 complex contains 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and probably 6 low-molecular weight proteins.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-201Cytochrome b/b6 N-terminal region profile
Domain202-369Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    369
  • Mass (Da)
    41,671
  • Last updated
    2002-06-01 v1
  • Checksum
    5385FE886C111E24
MSNQHKLLTFNLLPVGTNISTWWNFGSMLLTCLGLQITTGFFLAIHYTANVNLAFSSIIHITRDVPSGWIMQNLHATGASMFFICIYTHIARGLYYGSYLNKGVWLSGTTLLIILMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTSLTTWLWGGFSINDPTLTRFFALHFILPFTIISVSSIHILLLHNEGSSNPLGTNSDIDKIPFHPYHSLKDTLMLTSLLTTLFIVMSFFPNLFNDPENFSKANPMVTPQHIKPEWYFLFAYGILRSVPNKLGGTLALIMSIAILTTAPFTHTSIFRPMTFRPITQPIFWTLIVTFMTITWAATKPVEPPFITISQTTSIMYFLFFIINPVFGWIENKITN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF471031
EMBL· GenBank· DDBJ
AAL83565.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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