Q8S9K3 · VAR3_ARATH

Function

function

Probable component of some protein complex required for chloroplast and palisade cell development (PubMed:15340011).
Involved in C-to-U editing of chloroplastic RNA. Controls a large number of chloroplastic editing sites. Binds the editing recognition trans-factors PCMP-H51/CRR28 and PCMP-H12/OTP82 (PubMed:25768119).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchloroplast
Cellular Componentchloroplast stroma
Molecular Functionmetal ion binding
Molecular FunctionmRNA binding
Biological Processchloroplast mRNA modification
Biological Processchloroplast organization
Biological ProcessmRNA processing

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Zinc finger protein VAR3, chloroplastic
  • Alternative names
    • Organelle Zinc finger 1
    • Protein VARIEGATED 3

Gene names

    • Name
      VAR3
    • Synonyms
      OZ1
    • ORF names
      MVA3.140, MVA3.15
    • Ordered locus names
      At5g17790

Organism names

  • Taxonomic identifier
  • Strains
    • cv. Landsberg erecta
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8S9K3
  • Secondary accessions
    • Q64M74
    • Q9FN73

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Plastid, chloroplast
Note: Localizes at punctuate loci in chloroplasts.

Keywords

Phenotypes & Variants

Disruption phenotype

Defects result in variegated plants that have leaves consisting of normal green and also white or yellow sectors in which chloroplast development is retarded or disrupted (PubMed:15340011, PubMed:25768119).
Mutant plants exhibit severe editing defects in chloroplastic transcripts (PubMed:25768119).

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 117 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, transit peptide.

TypeIDPosition(s)Description
ChainPRO_0000022653?-758Zinc finger protein VAR3, chloroplastic
Transit peptide1-?Chloroplast

Proteomic databases

PTM databases

Expression

Tissue specificity

Weakly expressed in leaves and roots.

Gene expression databases

Interaction

Subunit

Interacts in vitro with the chloroplast-located protein CCD4/NCED4 (PubMed:15340011).
Homodimer. Interacts with ORRM1. Interacts with PCMP-H51/CRR28 and PCMP-H12/OTP82 (PubMed:25768119).
Interacts with ORRM6 (PubMed:28213559).

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY Q8S9K3CCD4 O496752EBI-632401, EBI-632411

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, zinc finger, repeat, compositional bias.

TypeIDPosition(s)Description
Region122-5023 X approximate repeat
Zinc finger276-305RanBP2-type 1
Zinc finger308-338RanBP2-type 2
Repeat368-4151
Region410-470Disordered
Compositional bias420-459Polar residues
Region512-545Disordered
Compositional bias523-545Basic and acidic residues
Repeat547-5962
Region572-606Disordered
Compositional bias573-598Basic and acidic residues
Region629-654Disordered
Compositional bias632-654Polar residues
Repeat688-7363
Region727-758Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    758
  • Mass (Da)
    85,945
  • Last updated
    2004-12-21 v2
  • Checksum
    5659AABF750BF8DE
MNNSTRLISLFSPHPPPLFLLRGLYISRIANLRRFHRRAFPPSSVASTNLCSFRPLVSLPPLIPTFPIGRFYNHQVRVSAADFVPSYHNQQLPEWTELLQSLSKAGYFSDSGSISGLESEFFPGFPDELLRPALACLALARERPELLEMLSRRDVEVLVENGKPFLFKTGPDSLKRMSLYLRSGLQGIGKLMDMEKASTVDLMRLILSYVVDVASSEESKQHNKEIMESSVRSLLSQIAKMSLRPPESNVHDTMQNQYSDRDGQGVRSFQNNVEMKRGDWICSRCSGMNFARNVKCFQCDEARPKRQLTGSEWECPQCDFYNYGRNVACLRCDCKRPRDSSLNSANSDYSSDPELERRLVENEKKAQRWLSKVAQGGSDANSVDTDEDFPEIMPLRKGVNRYVVSTRKPPLERRLANTENRVATDGNSKRSDDNALGSKTTRSLNEILGSSSSLTSRSDDKNVSSRRFESSQGINTDFVPFVPLPSDMFAKKPKEETQIGLIDNIQVDGFSGGNQNVYQEDKSDANHSGKETDRLEKEDHKSEEPARWFKRVTELHNVSDLESAIPQEISPEKMPMRKGENRFVVSRKKDRSLTSPAYKRPEDSDFVPFVPFPPDYFAKEKQPKESIDTLPAPATENVSQVVQQEPREPSINKSDTVAVKIRNGKSLEGSLVKESDLLDMSEEAKAERWFKRVAEIKNISELSEIPDEDFPSIMPMRKGVNRFVVSKRKTPLERRLTSQRHQRNPHITNSDPTGKGDK

Features

Showing features for sequence conflict, compositional bias.

TypeIDPosition(s)Description
Sequence conflict29in Ref. 1; AAL09834
Sequence conflict52-53in Ref. 1; AAL09834
Sequence conflict68in Ref. 1; AAL09834
Sequence conflict73in Ref. 1; AAL09834
Sequence conflict82in Ref. 1; AAL09834
Sequence conflict89in Ref. 1; AAL09834
Sequence conflict158in Ref. 1; AAL09834
Sequence conflict168in Ref. 1; AAL09834
Sequence conflict178in Ref. 1; AAL09834
Sequence conflict185in Ref. 1; AAL09834
Sequence conflict188in Ref. 1; AAL09834
Sequence conflict191in Ref. 1; AAL09834
Sequence conflict206in Ref. 1; AAL09834
Sequence conflict214in Ref. 1; AAL09834
Sequence conflict219-224in Ref. 1; AAL09834
Sequence conflict239in Ref. 1; AAL09834
Sequence conflict252in Ref. 1; AAL09834
Sequence conflict265in Ref. 1; AAL09834
Sequence conflict340in Ref. 1; AAL09834
Sequence conflict348in Ref. 1; AAL09834
Sequence conflict351in Ref. 1; AAL09834
Sequence conflict357in Ref. 1; AAL09834
Sequence conflict370in Ref. 1; AAL09834
Sequence conflict409in Ref. 1; AAL09834
Compositional bias420-459Polar residues
Sequence conflict421in Ref. 1; AAL09834
Sequence conflict427in Ref. 1; AAL09834
Sequence conflict502in Ref. 1; AAL09834
Sequence conflict505-510in Ref. 1; AAL09834
Compositional bias523-545Basic and acidic residues
Sequence conflict546in Ref. 1; AAL09834
Sequence conflict565in Ref. 1; AAL09834
Compositional bias573-598Basic and acidic residues
Sequence conflict579in Ref. 1; AAL09834
Sequence conflict621-626in Ref. 1; AAL09834
Sequence conflict630in Ref. 1; AAL09834
Compositional bias632-654Polar residues
Sequence conflict637in Ref. 1; AAL09834
Sequence conflict646in Ref. 1; AAL09834
Sequence conflict649-651in Ref. 1; AAL09834
Sequence conflict655-656in Ref. 1; AAL09834
Sequence conflict659-660in Ref. 1; AAL09834
Sequence conflict666in Ref. 4; AAL77653/AAN72244
Sequence conflict675in Ref. 1; AAL09834
Sequence conflict749in Ref. 1; AAL09834

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY050223
EMBL· GenBank· DDBJ
AAL09834.1
EMBL· GenBank· DDBJ
mRNA
AB006706
EMBL· GenBank· DDBJ
BAB09578.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED92469.1
EMBL· GenBank· DDBJ
Genomic DNA
AY075645
EMBL· GenBank· DDBJ
AAL77653.1
EMBL· GenBank· DDBJ
mRNA
BT002233
EMBL· GenBank· DDBJ
AAN72244.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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