Q8S8I4 · EPF1_ARATH

Function

function

Controls stomatal patterning. Regulates asymmetric cell division during guard cell differentiation. Mediates stomatal development inhibition. Not cleaved by the protease CRSP (AC Q9LNU1) (PubMed:25043023).
MEPF1: mobile signal controlling stomatal development in a non-cell-autonomous manner (PubMed:22241782).
Uses ERL1 as major receptor (PubMed:22241782).
May act by competing with somatogen (AC Q9SV72) for the same receptor, TMM (AC Q9SSD1) (PubMed:22027592).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular region
Biological Processnegative regulation of stomatal complex development
Biological Processstomatal complex development
Biological Processstomatal complex patterning

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Protein EPIDERMAL PATTERNING FACTOR 1
  • Cleaved into 1 chains

Gene names

    • Name
      EPF1
    • ORF names
      F5H14
    • Ordered locus names
      At2g20875

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8S8I4

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Increased stomatal density and violation of the one-cell-spacing rule (clustering of stomata).

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 5 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, glycosylation.

TypeIDPosition(s)Description
Signal1-20
ChainPRO_000039249721-104Protein EPIDERMAL PATTERNING FACTOR 1
ChainPRO_000043050553-104MEPF1
Disulfide bond60↔94
Disulfide bond64↔70
Disulfide bond67↔96
Disulfide bond79↔88
Glycosylation98N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in shoots, but not in roots. Mostly localized in developing leaves, specifically in meristemoids, guard mother cells (GMCs), and young guard cells.

Induction

Not induced by high CO2.

Gene expression databases

Interaction

Subunit

Interacts with ERECTA and ERL1, but not with TMM.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    104
  • Mass (Da)
    11,444
  • Last updated
    2002-06-01 v1
  • Checksum
    1B7FC910706F78C1
MKSLLLLAFFLSFFFGSLLARHLPTSSHPSHHHVGMTGALKRQRRRPDTVQVAGSRLPDCSHACGSCSPCRLVMVSFVCASVEEAETCPMAYKCMCNNKSYPVP

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC006234
EMBL· GenBank· DDBJ
AAM15214.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC07090.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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