Q8S8D3 · EREL2_ARATH
- ProteinPX domain-containing protein EREL2
- GeneEREL2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids643 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Acts as an effector of RABF2A and RABF2B (By similarity).
Involved in vacuolar transport of storage proteins. Regulates membrane trafficking to protein storage vacuoles (PSVs) (Probable). Binds specifically to phosphatidylinositol 3-monophosphate (PtdIns3P) (By similarity).
Involved in vacuolar transport of storage proteins. Regulates membrane trafficking to protein storage vacuoles (PSVs) (Probable). Binds specifically to phosphatidylinositol 3-monophosphate (PtdIns3P) (By similarity).
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | cytosol | |
Cellular Component | endosome membrane | |
Molecular Function | phosphatidylinositol binding | |
Biological Process | protein transport |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended namePX domain-containing protein EREL2
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ8S8D3
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Endosome membrane ; Peripheral membrane protein
Note: The endosomal localization depends on the active state of RABF2B.
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
No visible phenotype under normal growth conditions.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 118 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000438486 | 1-643 | PX domain-containing protein EREL2 | |||
Sequence: MQRRSPPKHRHDGASPLPLGMDWSPPPRNWNGRDTIWPHDFRTGWSYCVTIPSWTLLSKSKNSDPIVFYRVQVSVQSPEGVSTMRGILRRFNDFVKLLADLKRAFPRKSFPSAPPKGFLRVKSRDMLEERRCSLEDWMTKLLSDIELARSVVVASFLELEATARSACQVVDQNASDSNDDGNSTSLSSLVHPNSGGSSLLSSDYGSDTAYETSELGSASLGQDDVSETDTGDLTLDEDLTNPTEKLVKFSMSNIDEGLSMSQTIIEQLEDFPKHRVHLGYANDITETNSYNGKASKGVFRANNDLRCRSESETSHSVMHDRKLSLESADGVSLLAGETSTSSILSSIVHSQLDVNHDISVGNLEIPGNGRIVLPLKMHSKLNRILLTMNERLLNSKTDMEDLIARLNQETAVKEYLNRKVDDLEVELETTKQRNKENLEQALMTERQSVTKMQWDMEELRQKTFEMELKLKSKEDGSSDSKTSGNSTISESHELLQEMDATKQQLEDLSRRYVELEAKSKADIKVLVREVKSLRRSHMEMEKELTRSLTEKSDTEKLLQQERIIVENTLEARRRLYSDCEILHDRLKVNNTNLSMDESSNNREDLSEVSNALQDQIEAQLLLGFDETASEDELRKIMADMYED |
Proteomic databases
PTM databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain, compositional bias, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-26 | Disordered | ||||
Sequence: MQRRSPPKHRHDGASPLPLGMDWSPP | ||||||
Domain | 47-164 | PX | ||||
Sequence: YCVTIPSWTLLSKSKNSDPIVFYRVQVSVQSPEGVSTMRGILRRFNDFVKLLADLKRAFPRKSFPSAPPKGFLRVKSRDMLEERRCSLEDWMTKLLSDIELARSVVVASFLELEATAR | ||||||
Compositional bias | 172-228 | Polar residues | ||||
Sequence: QNASDSNDDGNSTSLSSLVHPNSGGSSLLSSDYGSDTAYETSELGSASLGQDDVSET | ||||||
Region | 172-239 | Disordered | ||||
Sequence: QNASDSNDDGNSTSLSSLVHPNSGGSSLLSSDYGSDTAYETSELGSASLGQDDVSETDTGDLTLDEDL | ||||||
Coiled coil | 389-440 | |||||
Sequence: NERLLNSKTDMEDLIARLNQETAVKEYLNRKVDDLEVELETTKQRNKENLEQ | ||||||
Coiled coil | 491-543 | |||||
Sequence: SHELLQEMDATKQQLEDLSRRYVELEAKSKADIKVLVREVKSLRRSHMEMEKE |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length643
- Mass (Da)72,823
- Last updated2002-06-01 v1
- ChecksumDA992D70213EF3D4
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1P8B1Z4 | A0A1P8B1Z4_ARATH | At2g25350 | 668 | ||
A0A1P8B1Z5 | A0A1P8B1Z5_ARATH | At2g25350 | 575 | ||
A0A1P8B237 | A0A1P8B237_ARATH | At2g25350 | 490 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 172-228 | Polar residues | ||||
Sequence: QNASDSNDDGNSTSLSSLVHPNSGGSSLLSSDYGSDTAYETSELGSASLGQDDVSET |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC007070 EMBL· GenBank· DDBJ | AAM15376.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC07692.1 EMBL· GenBank· DDBJ | Genomic DNA |