Q8S3D5 · LRL2_ARATH

Function

function

Transcription factor that regulates the development of root hairs (PubMed:19675148).
Transcription factor that regulates the development of sperm cells (PubMed:28585562).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA binding
Molecular FunctionDNA-binding transcription factor activity
Molecular Functionprotein dimerization activity
Biological Processmicrogametogenesis
Biological Processpollen sperm cell differentiation
Biological Processregulation of DNA-templated transcription
Biological Processroot hair cell development
Biological Processroot hair cell differentiation
Biological Processroot hair elongation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Transcription factor LRL2
  • Alternative names
    • Basic helix-loop-helix protein 69
      (AtbHLH69
      ; bHLH 69
      )
    • Protein DEFECTIVE REGION OF POLLEN 2
    • Protein LJRHL1- LIKE 2
      (AtLRL2
      )
    • Transcription factor EN 94
    • Transcription factor bHLH69
    • bHLH transcription factor bHLH069

Gene names

    • Name
      LRL2
    • Synonyms
      BHLH69
      , DROP2
      , EN94
    • ORF names
      F6I18.110
    • Ordered locus names
      At4g30980

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8S3D5
  • Secondary accessions
    • A0A178UUJ2
    • C0SVK8
    • O65552

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

No visible phenotype under normal growth conditions (PubMed:19675148, PubMed:28585562).
The triple mutant lrl1, lrl2 and lrl3 exhibit very short root hairs (PubMed:19675148).
The double mutant drop1 and drop2 fail to develop sperm cells (PubMed:28585562).

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 17 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003587631-310Transcription factor LRL2

Proteomic databases

Expression

Tissue specificity

Expressed constitutively in roots, leaves, stems, and flowers.

Induction

Repressed by heat treatment.

Gene expression databases

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias1-19Polar residues
Region1-23Disordered
Compositional bias95-124Polar residues
Region95-143Disordered
Region136-149Basic motif; degenerate
Domain136-185bHLH
Region150-185Helix-loop-helix motif
Region203-225Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    310
  • Mass (Da)
    32,880
  • Last updated
    2008-12-16 v2
  • MD5 Checksum
    2BA0A8FB07489E43AE046C669C4FC002
MNSSSLLTPSSSPSPHLQSPATFDHDDFLHHIFSSTPWPSSVLDDTPPPTSDCAPVTGFHHHDADSRNQITMIPLSHNHPNDALFNGFSTGSLPFHLPQGSGGQTQTQSQATASATTGGATAQPQTKPKVRARRGQATDPHSIAERLRRERIAERMKSLQELVPNGNKTDKASMLDEIIDYVKFLQLQVKVLSMSRLGGAASASSQISEDAGGSHENTSSSGEAKMTEHQVAKLMEEDMGSAMQYLQGKGLCLMPISLATTISTATCPSRSPFVKDTGVPLSPNLSTTIVANGNGSSLVTVKDAPSVSKP

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1P8B7F0A0A1P8B7F0_ARATHLRL2358

Sequence caution

The sequence CAA18195.1 differs from that shown. Reason: Erroneous gene model prediction
The sequence CAB79816.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-19Polar residues
Compositional bias95-124Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF488601
EMBL· GenBank· DDBJ
AAM10956.1
EMBL· GenBank· DDBJ
mRNA
AB493711
EMBL· GenBank· DDBJ
BAH30549.1
EMBL· GenBank· DDBJ
mRNA
AL022198
EMBL· GenBank· DDBJ
CAA18195.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
AL161578
EMBL· GenBank· DDBJ
CAB79816.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002687
EMBL· GenBank· DDBJ
AEE85837.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help