Q8RXV3 · P2C59_ARATH

Function

function

Protein phosphatase that modulates defense response to pathogenic bacteria, conferring resistance and promoting salicylic acid (SA) accumulation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 2 magnesium or manganese ions per subunit.

Activity regulation

Inhibited by sodium fluoride (NaF).

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site69Mn2+ 1 (UniProtKB | ChEBI)
Binding site69Mn2+ 2 (UniProtKB | ChEBI)
Binding site70Mn2+ 1 (UniProtKB | ChEBI)
Binding site231Mn2+ 2 (UniProtKB | ChEBI)
Binding site270Mn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionmetal ion binding
Molecular Functionmyosin phosphatase activity
Molecular Functionprotein serine/threonine phosphatase activity
Biological Processdefense response to bacterium
Biological Processprotein dephosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable protein phosphatase 2C 59
  • EC number
  • Short names
    AtPP2C59
  • Alternative names
    • HopW1-1-interacting protein 2
    • Protein phosphatase 2C WIN2 (PP2C WIN2)

Gene names

    • Name
      WIN2
    • ORF names
      F28M20.60
    • Ordered locus names
      At4g31750

Organism names

  • Taxonomic identifier
  • Strains
    • cv. Wassilewskija
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8RXV3
  • Secondary accessions
    • O81773

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003679811-311Probable protein phosphatase 2C 59

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Subunit

Interacts with the Pseudomonas syringae pv. maculicola effector HopW1-1 (via C-terminus).

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-26Disordered
Domain33-279PPM-type phosphatase

Sequence similarities

Belongs to the PP2C family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    311
  • Mass (Da)
    33,248
  • Last updated
    2002-06-01 v1
  • Checksum
    5E3098E91F116BFD
MGYLNSVLSSSSQVHSDDGPVSGGGLSQNGKFSYGYASSPGKRSSMEDFYETRIDGVEGEIVGLFGVFDGHGGARAAEYVKQNLFSNLIRHPKFISDTTAAIADAYNQTDSEFLKSENSQNRDAGSTASTAILVGDRLLVANVGDSRAVICRGGNAIAVSRDHKPDQSDERQRIEDAGGFVMWAGTWRVGGVLAVSRAFGDRLLKQYVVADPEIQEEKVDSSLEFLILASDGLWDVVSNEEAVGMIKAIEDPEEGAKRLMMEAYQRGSADNITCVVVRFFSDQAGGIGSSSTNIPIDHGIVPDRISGDSST

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1P8B4X7A0A1P8B4X7_ARATHWIN2305

Sequence caution

The sequence CAA19748.1 differs from that shown. Reason: Erroneous gene model prediction
The sequence CAB79893.1 differs from that shown. Reason: Erroneous gene model prediction

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EU214909
EMBL· GenBank· DDBJ
ABW84225.1
EMBL· GenBank· DDBJ
mRNA
AL031004
EMBL· GenBank· DDBJ
CAA19748.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
AL161579
EMBL· GenBank· DDBJ
CAB79893.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002687
EMBL· GenBank· DDBJ
AEE85953.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
ANM66655.1
EMBL· GenBank· DDBJ
Genomic DNA
AY080658
EMBL· GenBank· DDBJ
AAL86334.1
EMBL· GenBank· DDBJ
mRNA
AY133761
EMBL· GenBank· DDBJ
AAM91695.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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