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Q8RXF8 · MIRO1_ARATH

Function

function

Mitochondrial GTPase required to maintain proper development, morphology and intracellular distribution of mitochondria, which in turn are essential for the progress of embryonic cell division, development of haploid male and female gametes, and pollen tube growth.

Features

Showing features for binding site.

164850100150200250300350400450500550600
TypeIDPosition(s)Description
Binding site211Ca2+ 1 (UniProtKB | ChEBI)
Binding site213Ca2+ 1 (UniProtKB | ChEBI)
Binding site215Ca2+ 1 (UniProtKB | ChEBI)
Binding site222Ca2+ 1 (UniProtKB | ChEBI)
Binding site332Ca2+ 2 (UniProtKB | ChEBI)
Binding site334Ca2+ 2 (UniProtKB | ChEBI)
Binding site336Ca2+ 2 (UniProtKB | ChEBI)
Binding site338Ca2+ 2 (UniProtKB | ChEBI)
Binding site343Ca2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial outer membrane
Cellular Componentmitochondrion
Cellular Componentplastid
Molecular Functioncalcium ion binding
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Biological Processembryo development ending in seed dormancy
Biological Processmitochondrion organization
Biological Processpollen tube growth

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mitochondrial Rho GTPase 1
  • EC number
  • Short names
    AtMIRO1
  • Alternative names
    • Miro-related GTPase 1

Gene names

    • Name
      MIRO1
    • Ordered locus names
      At5g27540

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8RXF8

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

Type
IDPosition(s)Description
Topological domain1-619Cytoplasmic
Transmembrane620-640Helical
Topological domain641-648Mitochondrial intermembrane

Keywords

Phenotypes & Variants

Disruption phenotype

Embryonic lethality between the apical 2-cell and the 4-terminal-cell embryo stage (PubMed:18344283, PubMed:20931334).
Impaired in pollen germination and pollen tube growth (PubMed:18344283).

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 26 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, modified residue.

Type
IDPosition(s)Description
ChainPRO_00004317151-648Mitochondrial Rho GTPase 1
Modified residue14Phosphoserine

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in roots, leaves, stems, flowers and siliques.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain15-182Miro 1
Domain198-233EF-hand 1
Domain319-354EF-hand 2
Domain427-595Miro 2

Sequence similarities

Belongs to the mitochondrial Rho GTPase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    648
  • Mass (Da)
    72,322
  • Last updated
    2002-06-01 v1
  • MD5 Checksum
    E770B4CD444F5C79093D5C110B93CB52
MARYAAGAVDCPGSPKSVRIVVVGDKGTGKSSLIVAAATDSFPPNVPPVLPDYKLPIEFFPDGIPVTIVDTSSRPEDRDIVAEELKRADAVVLTYACDRPETLERLSEYWLPELRRLEVKIPIIVAGCKLDFRDDNNQVSLEQVMSPIMQQFREIETCIECSALKQLQAQEVFYYAQKTVLHPTGPLFDQDSQALKPRCVRALKRIFILCDHDRDGALSEAELNDFQVKCFHAPLQPSEIEGVKRVVQEKLPEGVNERGLTVTGFLFLHALFIEKGRLETTWTVLRKFGYNNDIRLAEELLPSAIFKRAPDQSFELTNAAIDFLKGMYMLFDDDQDNNLRPQEIEDLFSTAPESPWKEAPYEDAAEKTALGGLSFDAFLSMWSLMTLLEPARSVENLIYIGFPGDPSTAIRVTRRRRLDRKKQQCERKVFQCFVFGPNNAGKSALLNCFLGRSYTDNQESTTDERYAVNMVDESGAKKTLIMREIPEDGVQGLFSSKESLAACDIAVFVYDSSDESSWKRATQLLVEVANYGEATGYEVPCLMVSAKDDLDSSPISIQESTRMTQDMGIEPPVSISSKLGDFNNLFRKILTAAQHPHLSIPETEAGKSRKHYNRLINRSLMAVSIGAAAVVVGLAAYRVYATRKSSSA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC007478
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CP002688
EMBL· GenBank· DDBJ
AED93698.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED93699.1
EMBL· GenBank· DDBJ
Genomic DNA
AY081280
EMBL· GenBank· DDBJ
AAL91169.1
EMBL· GenBank· DDBJ
mRNA
BT003352
EMBL· GenBank· DDBJ
AAO29970.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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