Q8RTZ8 · Q8RTZ8_9GAMM
- ProteinRibonuclease H
- GenernhA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids157 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Catalytic activity
Cofactor
Note: Binds 1 Mg2+ ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | magnesium ion binding | |
Molecular Function | nucleic acid binding | |
Molecular Function | RNA-DNA hybrid ribonuclease activity | |
Biological Process | RNA catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibonuclease H
- EC number
- Short namesRNase H
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Shewanellaceae > Shewanella
Accessions
- Primary accessionQ8RTZ8
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 3-144 | RNase H type-1 | ||||
Sequence: ELKQLYIFTDGSCLGNPGPGGYGVVMKYKHQQHEIADGFSLTTNNRMELLAPIIALETLYEPCNIILTSDSQYMRQGIMTWIHGWKKKGWITSTKQPVKNVDLWKRLDAVSQLHKIDWHWVKGHAGHIENERCDVLARKAAE |
Sequence similarities
Belongs to the RNase H family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length157
- Mass (Da)17,890
- Last updated2002-06-01 v1
- ChecksumBE10C3D84FB409BC