Q8RTZ8 · Q8RTZ8_9GAMM

  • Protein
    Ribonuclease H
  • Gene
    rnhA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

Catalytic activity

  • Endonucleolytic cleavage to 5'-phosphomonoester.
    EC:3.1.26.4 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.

Features

Showing features for binding site.

115720406080100120140
TypeIDPosition(s)Description
Binding site12Mg2+ 1 (UniProtKB | ChEBI)
Binding site12Mg2+ 2 (UniProtKB | ChEBI)
Binding site50Mg2+ 1 (UniProtKB | ChEBI)
Binding site72Mg2+ 1 (UniProtKB | ChEBI)
Binding site136Mg2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionmagnesium ion binding
Molecular Functionnucleic acid binding
Molecular FunctionRNA-DNA hybrid ribonuclease activity
Biological ProcessRNA catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribonuclease H
  • EC number
  • Short names
    RNase H

Gene names

    • Name
      rnhA

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SIB1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Shewanellaceae > Shewanella

Accessions

  • Primary accession
    Q8RTZ8

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-144RNase H type-1

Sequence similarities

Belongs to the RNase H family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    157
  • Mass (Da)
    17,890
  • Last updated
    2002-06-01 v1
  • Checksum
    BE10C3D84FB409BC
MAELKQLYIFTDGSCLGNPGPGGYGVVMKYKHQQHEIADGFSLTTNNRMELLAPIIALETLYEPCNIILTSDSQYMRQGIMTWIHGWKKKGWITSTKQPVKNVDLWKRLDAVSQLHKIDWHWVKGHAGHIENERCDVLARKAAEAKPQQVDTGYNPE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB070445
EMBL· GenBank· DDBJ
BAB85475.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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