Q8RKI9 · TARI_BACSH
- ProteinRibitol-5-phosphate cytidylyltransferase
- GenetarI
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids237 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
Catalytic activity
- D-ribitol 5-phosphate + CTP + H+ = CDP-L-ribitol + diphosphate
Pathway
Cell wall biogenesis; poly(ribitol phosphate) teichoic acid biosynthesis.
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 7-10 | CTP (UniProtKB | ChEBI) | ||||
Sequence: LAGG | ||||||
Site | 14 | Transition state stabilizer | ||||
Sequence: R | ||||||
Site | 22 | Transition state stabilizer | ||||
Sequence: K | ||||||
Binding site | 81-87 | CTP (UniProtKB | ChEBI) | ||||
Sequence: GSDRNES | ||||||
Binding site | 112 | CTP (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Site | 160 | Positions ribitol 5-phosphate for the nucleophilic attack | ||||
Sequence: R | ||||||
Site | 217 | Positions ribitol 5-phosphate for the nucleophilic attack | ||||
Sequence: K |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity | |
Molecular Function | D-ribitol-5-phosphate cytidylyltransferase activity | |
Biological Process | cell wall organization | |
Biological Process | isoprenoid biosynthetic process | |
Biological Process | poly(ribitol phosphate) teichoic acid biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibitol-5-phosphate cytidylyltransferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus
Accessions
- Primary accessionQ8RKI9
- Secondary accessions
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000075685 | 1-237 | Ribitol-5-phosphate cytidylyltransferase | |||
Sequence: MIYAEILAGGKGSRMGNVNMPKQFLPLNKRPIIIHTVEKFLLNDRFDKILIVSPKEWINHTKDILKKFIGQDDRLVVVEGGSDRNESIMSGIRYIEKEFGIQDNDVIITHDSVRPFLTHRIIDENIDAVLQYGAVDTVISAIDTIIASEDQEFISDIPVRDNMYQGQTPQSFRISKLVELYNKLSDEQKAVLTDACKICSLAGEKVKLVRGEVFNIKVTTPYDLKVANAILQERISQ |
Structure
Sequence
- Sequence statusComplete
- Length237
- Mass (Da)26,848
- Last updated2002-06-01 v1
- Checksum0B03F2F41D6CE5AB
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AJ313428 EMBL· GenBank· DDBJ | CAC86109.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AM260209 EMBL· GenBank· DDBJ | CAJ97396.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002183 EMBL· GenBank· DDBJ | ADM39548.1 EMBL· GenBank· DDBJ | Genomic DNA |