Q8RDX7 · TPIS_FUSNN
- ProteinTriosephosphate isomerase
- GenetpiA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids251 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
Catalytic activity
- D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 9-11 | substrate | |||
Active site | 95 | Electrophile | |||
Active site | 167 | Proton acceptor | |||
Binding site | 173 | substrate | |||
Binding site | 213 | substrate | |||
Binding site | 234-235 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | triose-phosphate isomerase activity | |
Biological Process | gluconeogenesis | |
Biological Process | glyceraldehyde-3-phosphate biosynthetic process | |
Biological Process | glycerol catabolic process | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTriosephosphate isomerase
- EC number
- Short namesTIM ; TPI
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Fusobacteriota > Fusobacteriia > Fusobacteriales > Fusobacteriaceae > Fusobacterium
Accessions
- Primary accessionQ8RDX7
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000090223 | 1-251 | Triosephosphate isomerase | ||
Proteomic databases
Interaction
Structure
Sequence
- Sequence statusComplete
- Length251
- Mass (Da)27,670
- Last updated2002-06-01 v1
- Checksum60374A495DF85A9E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE009951 EMBL· GenBank· DDBJ | AAL95562.1 EMBL· GenBank· DDBJ | Genomic DNA |