Q8RA23 · PYRH_CALS4
- ProteinUridylate kinase
- GenepyrH
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids237 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible phosphorylation of UMP to UDP.
Catalytic activity
- UMP + ATP = UDP + ADP
Activity regulation
Inhibited by UTP.
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 12-15 | ATP (UniProtKB | ChEBI) | |||
Binding site | 54 | UMP (UniProtKB | ChEBI) | |||
Binding site | 55 | ATP (UniProtKB | ChEBI) | |||
Binding site | 59 | ATP (UniProtKB | ChEBI) | |||
Binding site | 72 | UMP (UniProtKB | ChEBI) | |||
Binding site | 133-140 | UMP (UniProtKB | ChEBI) | |||
Binding site | 166 | ATP (UniProtKB | ChEBI) | |||
Binding site | 169 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | UMP kinase activity | |
Biological Process | 'de novo' CTP biosynthetic process | |
Biological Process | phosphorylation | |
Biological Process | UDP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridylate kinase
- EC number
- Short namesUK
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Thermoanaerobacterales > Thermoanaerobacteraceae > Caldanaerobacter
Accessions
- Primary accessionQ8RA23
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000143901 | 1-237 | Uridylate kinase | ||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length237
- Mass (Da)25,789
- Last updated2002-06-01 v1
- Checksum93F6E495E73EEB6A
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE008691 EMBL· GenBank· DDBJ | AAM24629.1 EMBL· GenBank· DDBJ | Genomic DNA |