Q8Q0M2 · TRUD_METMA
- ProteinProbable tRNA pseudouridine synthase D
- GenetruD
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids438 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
Catalytic activity
- uridine13 in tRNA = pseudouridine13 in tRNA
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 86 | Nucleophile | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | RNA binding | |
Molecular Function | tRNA pseudouridine(13) synthase activity | |
Biological Process | tRNA pseudouridine synthesis |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable tRNA pseudouridine synthase D
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Methanomicrobia > Methanosarcinales > Methanosarcinaceae > Methanosarcina
Accessions
- Primary accessionQ8Q0M2
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000152543 | 1-438 | Probable tRNA pseudouridine synthase D | |||
Sequence: MEVPEIEKQIGINLYSTDTTGLGGQLRQEIEDFIVKEITNREEGEEGKYLIVELTKRDWDTHHLTRTLSRILQVSQKRISVAGTKDKRALTTQKISIFDTDASEIEKIHLKDIELKVLGRSRKSVELGDLWGNDFRITVRNIENSPEETEALLKKTTDEILAQGGVPNFFGIQRFGSVRPVTHLVGKAIVEGNFEKAALLYIAEPFPEEPEETKNARQFVKDTLDFKEGLKTYPLRLGHERAMMNHLIANPEDYSGSFRVLPQNLYRMFVHGYQSYIYNIILCRRIEAGIPLNRAVEGDIVCFRNEVGLPDSSKTEKVTSETVNAMNRLLKLGRAFITAPLPGYNTEFASGIPGEIENGVLKELGVSLEGFNIEKFPEMSSKGTRREVLLEVKPKFEAGEDELNPGKSKAVLEFMLPKGSYATTVLREYMKVNPLQMS |
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 165-390 | TRUD | ||||
Sequence: GVPNFFGIQRFGSVRPVTHLVGKAIVEGNFEKAALLYIAEPFPEEPEETKNARQFVKDTLDFKEGLKTYPLRLGHERAMMNHLIANPEDYSGSFRVLPQNLYRMFVHGYQSYIYNIILCRRIEAGIPLNRAVEGDIVCFRNEVGLPDSSKTEKVTSETVNAMNRLLKLGRAFITAPLPGYNTEFASGIPGEIENGVLKELGVSLEGFNIEKFPEMSSKGTRREVLL |
Sequence similarities
Belongs to the pseudouridine synthase TruD family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length438
- Mass (Da)49,499
- Last updated2002-10-01 v1
- ChecksumD8404CC1672C0016
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE008384 EMBL· GenBank· DDBJ | AAM29810.1 EMBL· GenBank· DDBJ | Genomic DNA |