Q8PC99 · PRMC_XANCP
- ProteinRelease factor glutamine methyltransferase
- GeneprmC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids283 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
Catalytic activity
- L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = N5-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 120-124 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 143 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 171 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 186 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 186-189 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | nucleic acid binding | |
Molecular Function | protein-(glutamine-N5) methyltransferase activity | |
Molecular Function | protein-glutamine N-methyltransferase activity | |
Biological Process | peptidyl-glutamine methylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRelease factor glutamine methyltransferase
- EC number
- Short namesRF MTase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Lysobacterales > Lysobacteraceae > Xanthomonas
Accessions
- Primary accessionQ8PC99
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000414550 | 1-283 | Release factor glutamine methyltransferase | ||
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length283
- Mass (Da)30,275
- Last updated2002-10-01 v1
- ChecksumA5F4E951E8E33479
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE008922 EMBL· GenBank· DDBJ | AAM40150.1 EMBL· GenBank· DDBJ | Genomic DNA |