Q8P6V8 · METXS_XANCP

Function

function

Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-succinyl-L-homoserine from L-homoserine: step 1/1.

Features

Showing features for active site, site, binding site.

136950100150200250300350
TypeIDPosition(s)Description
Active site172Nucleophile
Site173Important for substrate specificity
Site209Important for acyl-CoA specificity
Binding site233substrate
Active site314
Active site344
Binding site345substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionhomoserine O-acetyltransferase activity
Molecular Functionhomoserine O-succinyltransferase activity
Biological Processhomoserine metabolic process
Biological Processmethionine biosynthetic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Homoserine O-succinyltransferase
  • EC number
  • Short names
    HST
  • Alternative names
    • Homoserine transsuccinylase
      (HTS
      )

Gene names

    • Name
      metXS
    • Ordered locus names
      XCC2857

Organism names

Accessions

  • Primary accession
    Q8P6V8
  • Secondary accessions
    • A0A1D3PD87

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004403051-369Homoserine O-succinyltransferase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-21Disordered
Domain86-350AB hydrolase-1
Region92-95Important for substrate specificity

Sequence similarities

Belongs to the AB hydrolase superfamily. MetX family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    369
  • Mass (Da)
    39,292
  • Last updated
    2017-06-07 v2
  • Checksum
    C7893D2D991C2328
MVRIVPSARRTRAPAKLDGRSTPDIAMSLVTTASPLTTADTYTPAADSDAPPAVRGELVINLPMRHAGQRELRLRYELVGAEQAPVVFVAGGISAHRHLAASAVFPEKGWVEGLVGAGRALDPASRRLLAFDFLGADGSLDAPIDTADQADAIAALLDALGIARLHGFVGYSYGALVGLQFASRHAARLHTLVAVSGAHRAHPYAAAWRALQRRAVALGQLQCAEHHGLALARQFAMLSYRTPEEFSERFDAPPELINGRVRVAAEDYLDAAGAQYVARTPVNAYLRLSESIDLHRIDPAAVAVPTVVVAVEGDRLVPLADLVSLVEGLGPRGSLRVLRSPFGHDAFLKEIDRIDAILTTALRTTGETA

Sequence caution

The sequence AAM42129.1 differs from that shown. Reason: Erroneous initiation Truncated N-terminus.

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LT613641
EMBL· GenBank· DDBJ
SCN13865.1
EMBL· GenBank· DDBJ
Genomic DNA
AE008922
EMBL· GenBank· DDBJ
AAM42129.1
EMBL· GenBank· DDBJ
Genomic DNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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