Q8NRY1 · RSMA_CORGL
- ProteinRibosomal RNA small subunit methyltransferase A
- GenersmA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids293 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
Catalytic activity
- adenosine1518/adenosine1519 in 16S rRNA + 4 S-adenosyl-L-methionine = N6-dimethyladenosine1518/N6-dimethyladenosine1519 in 16S rRNA + 4 S-adenosyl-L-homocysteine + 4 H+
RHEA-COMP:10232 CHEBI:74411 Position: 1518CHEBI:74411 Position: 1519+ 4 CHEBI:59789 = RHEA-COMP:10233 CHEBI:74493 Position: 1518CHEBI:74493 Position: 1519+ 4 CHEBI:57856 + 4 CHEBI:15378
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 33 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 35 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 60 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 81 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 111 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 130 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity | |
Molecular Function | RNA binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibosomal RNA small subunit methyltransferase A
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Corynebacteriaceae > Corynebacterium
Accessions
- Primary accessionQ8NRY1
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000101519 | 1-293 | Ribosomal RNA small subunit methyltransferase A | ||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length293
- Mass (Da)31,774
- Last updated2002-10-01 v1
- MD5 Checksum8F9F5C047F969DC225BD5F8333AC55A2
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BA000036 EMBL· GenBank· DDBJ | BAB98303.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BX927150 EMBL· GenBank· DDBJ | CAF19616.1 EMBL· GenBank· DDBJ | Genomic DNA |