Q8NPB7 · AFTC_CORGL
- ProteinAlpha-(1->3)-arabinofuranosyltransferase
- GeneaftC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids418 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the corynebacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG.
Catalytic activity
Pathway
Cell wall biogenesis; cell wall polysaccharide biosynthesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | hexosyltransferase activity | |
Biological Process | capsule polysaccharide biosynthetic process | |
Biological Process | cell wall organization |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlpha-(1->3)-arabinofuranosyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Corynebacteriaceae > Corynebacterium
Accessions
- Primary accessionQ8NPB7
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 25-45 | Helical | ||||
Sequence: NAVAWPLAMLLMAHRFFVLAI | ||||||
Transmembrane | 81-101 | Helical | ||||
Sequence: YLYNPGATLLLAPLGYITHFT | ||||||
Transmembrane | 102-122 | Helical | ||||
Sequence: LARWMFIAVNLLAIVLAFGLL | ||||||
Transmembrane | 125-145 | Helical | ||||
Sequence: LSGWALRSMVWPIAIALAMLT | ||||||
Transmembrane | 153-173 | Helical | ||||
Sequence: IFSNINGILLLMLAIFLWCVV | ||||||
Transmembrane | 183-203 | Helical | ||||
Sequence: VIGLAILIKPMFLPLLFLPLV | ||||||
Transmembrane | 210-230 | Helical | ||||
Sequence: LILGILTPVIFNAVAWFLVPG | ||||||
Transmembrane | 266-286 | Helical | ||||
Sequence: MEITWFLIFGAMVGLAVLALL | ||||||
Transmembrane | 293-312 | Helical | ||||
Sequence: PYFWAATTTGVLLTGVFFLS | ||||||
Transmembrane | 327-349 | Helical | ||||
Sequence: IFTLLGSRSVFHNWVAWVAAYFF | ||||||
Transmembrane | 372-392 | Helical | ||||
Sequence: ATVGWGLLIVVTFVSALIWFI |
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Cells lacking this gene show reduced levels of cell wall-bound corynomycolic acid methyl esters (CMAMEs).
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000451751 | 1-418 | Alpha-(1->3)-arabinofuranosyltransferase | |||
Sequence: MSFSPVAPSISAPTPRRSRWDSIGNAVAWPLAMLLMAHRFFVLAINGAVTDDFTTVYSALRRFVEGIPVYNEVYHFVDPHYLYNPGATLLLAPLGYITHFTLARWMFIAVNLLAIVLAFGLLTRLSGWALRSMVWPIAIALAMLTETVQNTLIFSNINGILLLMLAIFLWCVVHKKSWLGGLVIGLAILIKPMFLPLLFLPLVKKQWGSLILGILTPVIFNAVAWFLVPGASEYVTRTMPYLGETRDFANSSLPGLAIYFGMPTWMEITWFLIFGAMVGLAVLALLRFRNTEPYFWAATTTGVLLTGVFFLSSLGQMYYSMMIFPMIFTLLGSRSVFHNWVAWVAAYFFLSPDTFTSQRLPDVARWMEFFSATVGWGLLIVVTFVSALIWFIGDIRAKGTPSSPITTDPTHDHLERTA |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length418
- Mass (Da)46,837
- Last updated2002-10-01 v1
- ChecksumDA1F4DC16E60A490
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BA000036 EMBL· GenBank· DDBJ | BAB99290.1 EMBL· GenBank· DDBJ | Genomic DNA |