Q8NMD7 · SYC_CORGL
- ProteinCysteine--tRNA ligase
- GenecysS
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids460 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- tRNA(Cys) + L-cysteine + ATP = L-cysteinyl-tRNA(Cys) + AMP + diphosphate
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 29 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 212 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 237 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 241 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 271 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | cysteine-tRNA ligase activity | |
Molecular Function | zinc ion binding | |
Biological Process | cysteinyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCysteine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Corynebacteriaceae > Corynebacterium
Accessions
- Primary accessionQ8NMD7
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000159388 | 1-460 | Cysteine--tRNA ligase | ||
Interaction
Structure
Family & Domains
Features
Showing features for motif.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Motif | 31-41 | 'HIGH' region | |||
Motif | 268-272 | 'KMSKS' region | |||
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length460
- Mass (Da)51,047
- Last updated2002-10-25 v1
- ChecksumC28B536BFC24C44A
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BA000036 EMBL· GenBank· DDBJ | BAC00035.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BX927155 EMBL· GenBank· DDBJ | CAF21303.1 EMBL· GenBank· DDBJ | Genomic DNA |