Q8NJQ5 · CHI37_TRIHA

Function

function

Secreted chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods). Plays a morphogenetic role during apical growth, cell division and differentiation (cell wall morphogenesis). May be involved in the degradation and further assimilation of phytopathogenic fungi, namely mycoparasitism, the major mechanism accounting for the antagonistic activity against phytopathogenic fungi displayed by Trichoderma.

Catalytic activity

  • Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.
    EC:3.2.1.14 (UniProtKB | ENZYME | Rhea)

Biotechnology

The antagonistic activity of Trichoderma harzianum is used for the control of several soil borne plant pathogenic fungi.

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
0.5 mg/mlcolloidal chitin
0.7 mMp-nitrophenyl-N-N'-diacetylchitobiose

Temperature Dependence

Optimum temperature is 45-50 degrees Celsius.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site160Proton donor

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular Functionchitin binding
Molecular Functionchitinase activity
Biological Processchitin catabolic process
Biological Processpolysaccharide catabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Endochitinase 37
  • EC number
  • Alternative names
    • 37 kDa endochitinase
    • Chitinase 37

Gene names

    • Name
      chit37

Organism names

  • Taxonomic identifier
  • Strain
    • ATCC 48131 / CBS 354.33 / CECT 2413 / VTT D-80150
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Hypocreaceae > Trichoderma

Accessions

  • Primary accession
    Q8NJQ5

Subcellular Location

Keywords

Phenotypes & Variants

PTM/Processing

Features

Showing features for signal, chain, glycosylation.

TypeIDPosition(s)Description
Signal1-25
ChainPRO_000042989426-337Endochitinase 37
Glycosylation331N-linked (GlcNAc...) asparagine

Keywords

PTM databases

Expression

Induction

Specifically induced by chitin.

Interaction

Subunit

Monomer.

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain38-337GH18

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    337
  • Mass (Da)
    35,478
  • Last updated
    2002-10-01 v1
  • Checksum
    0C9B50F416897EF1
MTRLLDASFLLLPVIASTLFGTASAQSTCATKGKPAGKVLQGYWENWDGSANGVHPGFGWTPIENPVIAQNGYNVINAAFPVILSDGTALWEDGMDATVKVATPAEMCQAKAAGATILMSIGGATAGIDLSSSTVADKFISTIVPILKQYNFDGIDIDIETGLVGSGSIGTLSTSQANLIRIIDGVLAQMPANFGLTMAPETAYVTGGSVVYGSIWGSYLPIIKKYVDNGRLWWLNMQYYNGDMYGCSGDSYAAGTVQGFTAQTDCLNNGITIQGTTIKVPYNMQVPGLPAQSGAGGGYMTPALVGQAWDHYNGALKGLMTWSINWDGSKNWTFGDN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF525753
EMBL· GenBank· DDBJ
AAM93195.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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