Q8NGA0 · OR7G1_HUMAN
- ProteinOlfactory receptor 7G1
- GeneOR7G1
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids311 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Odorant receptor.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | G protein-coupled receptor activity | |
Molecular Function | olfactory receptor activity | |
Biological Process | signal transduction |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameOlfactory receptor 7G1
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ8NGA0
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-29 | Extracellular | ||||
Sequence: MGPRNQTAVSEFLLMKVTEDPELKLIPFS | ||||||
Transmembrane | 30-50 | Helical; Name=1 | ||||
Sequence: LFLSMYLVTILGNLLILLAVI | ||||||
Topological domain | 51-57 | Cytoplasmic | ||||
Sequence: SDSHLHT | ||||||
Transmembrane | 58-78 | Helical; Name=2 | ||||
Sequence: PMYFLLFNLSFTDICLTTTTV | ||||||
Topological domain | 79-97 | Extracellular | ||||
Sequence: PKILVNIQAQNQSITYTGC | ||||||
Transmembrane | 98-118 | Helical; Name=3 | ||||
Sequence: LTQICLVLVFAGLESCFLAVM | ||||||
Topological domain | 119-133 | Cytoplasmic | ||||
Sequence: AYDRYVAICHPLRYT | ||||||
Transmembrane | 134-154 | Helical; Name=4 | ||||
Sequence: VLMNVHFWGLLILLSMFMSTM | ||||||
Topological domain | 155-196 | Extracellular | ||||
Sequence: DALVQSLMVLQLSFCKNVEIPLFFCEVVQVIKLACSDTLINN | ||||||
Transmembrane | 197-217 | Helical; Name=5 | ||||
Sequence: ILIYFASSVFGAIPLSGIIFS | ||||||
Topological domain | 218-244 | Cytoplasmic | ||||
Sequence: YSQIVTSVLRMPSARGKYKAFSTCGCH | ||||||
Transmembrane | 245-265 | Helical; Name=6 | ||||
Sequence: LSVFSLFYGTAFGVYISSAVA | ||||||
Topological domain | 266-269 | Extracellular | ||||
Sequence: ESSR | ||||||
Transmembrane | 270-290 | Helical; Name=7 | ||||
Sequence: ITAVASVMYTVVPQMMNPFIY | ||||||
Topological domain | 291-311 | Cytoplasmic | ||||
Sequence: SLRNKEMKKALRKLIGRLFPF |
Keywords
- Cellular component
Disease & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | VAR_048074 | 83 | in dbSNP:rs6511874 | |||
Sequence: V → A | ||||||
Natural variant | VAR_034255 | 141 | in dbSNP:rs2217657 | |||
Sequence: W → C | ||||||
Natural variant | VAR_048075 | 156 | in dbSNP:rs7246980 | |||
Sequence: A → V | ||||||
Natural variant | VAR_048076 | 167 | in dbSNP:rs7246969 | |||
Sequence: S → F | ||||||
Natural variant | VAR_034256 | 252 | in dbSNP:rs2195951 | |||
Sequence: Y → C |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 382 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain, glycosylation, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000150650 | 1-311 | Olfactory receptor 7G1 | |||
Sequence: MGPRNQTAVSEFLLMKVTEDPELKLIPFSLFLSMYLVTILGNLLILLAVISDSHLHTPMYFLLFNLSFTDICLTTTTVPKILVNIQAQNQSITYTGCLTQICLVLVFAGLESCFLAVMAYDRYVAICHPLRYTVLMNVHFWGLLILLSMFMSTMDALVQSLMVLQLSFCKNVEIPLFFCEVVQVIKLACSDTLINNILIYFASSVFGAIPLSGIIFSYSQIVTSVLRMPSARGKYKAFSTCGCHLSVFSLFYGTAFGVYISSAVAESSRITAVASVMYTVVPQMMNPFIYSLRNKEMKKALRKLIGRLFPF | ||||||
Glycosylation | 5 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 89 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Disulfide bond | 97↔179 | |||||
Sequence: CLTQICLVLVFAGLESCFLAVMAYDRYVAICHPLRYTVLMNVHFWGLLILLSMFMSTMDALVQSLMVLQLSFCKNVEIPLFFC |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Structure
Sequence
- Sequence statusComplete
- Length311
- Mass (Da)34,803
- Last updated2008-12-16 v2
- ChecksumC408FFF590A95340
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB065926 EMBL· GenBank· DDBJ | BAC06141.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
AC011464 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AF399538 EMBL· GenBank· DDBJ | AAK95023.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BK004267 EMBL· GenBank· DDBJ | DAA04665.1 EMBL· GenBank· DDBJ | Genomic DNA |