Q8NCX0 · CC150_HUMAN
- ProteinCoiled-coil domain-containing protein 150
- GeneCCDC150
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids1101 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCoiled-coil domain-containing protein 150
Gene names
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Hominoidea (apes) > Hominidae (great apes) > Homininae > Homo
Accessions
- Primary accessionQ8NCX0
- Secondary accessions
Proteomes
Organism-specific databases
Disease & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | VAR_042600 | 156 | in dbSNP:rs34133636 | |||
Sequence: E → K |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 1,248 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000328984 | 1-1101 | Coiled-coil domain-containing protein 150 | |||
Sequence: MDCKVHMETTVSRPVLSPTHINATASETFTVLQQRMRIVEEQTSSLRDDLIMLDFGEKRGYLEAPDCLEDLDSQKVISPIQNEAICAGKTDILWKNCEFLVNRMCRLESLMQSLKMNIFRLQTEKDLNPQKTAFLKDRLNAIQEEHSKDLKLLHLEVMNLRQQLRAVKEEEDKAQDEVQRLTATLKIASQTKKNAAIIEEELKTTKRKMNLKIQELRRQLAQEKYLRESLEKSASAMLLKIQEMGSTVEVERKQVHILQQNCIALRDSIQSAQELLAQEQKKKEELEIATSQLKSDLTSRDDLISKLVEENKNLQISFNKEHEENAYLRSEIMSLHEASEKAQVLNDQLTKKCSELSCMLQTVTMEKARIIADHQAILQVEQKMMTQTFQEQNLLLDAAHASITNELQTVQNEKTQLQAHLDHLILEHNQCIQKAQDAEKRTAVQKELLESTIARLRGELEASMQEKKSLLEEKERFQREVNKTEKEIVQERCNLEKELAKNKVDINTLTHNLQTLEEENKHLADQMASLELQQVTSDYHGLAQQKVEKITESKNKLAYENGKLQIKVKQLEEQVQSFTDTSLQNDHLRKMNKYLQTKYAQANSELSAKRVHLQQADAHLKEVKSILERSKEELSRTVKCRNAALKESQKLKEDLEAVEDRENKKVGNFQRQLAEAKEDNCKVTIMLENVLASHSKMQGALEKVQIELGRRDSEIAGLKKERDLNQQRVQKLEAEVDQWQARMLVMEDQHNSEIESLQKALGVAREDNRKLAMSLEQALQTNNHLQTKLDHIQEQLESKELERQNLETFKDRMTEESKVEAELHAERIEALRKQFQTERETTKKVAQREVAELKKALDEANFRSVEVSRTNRELRQKLAELEKILESNKEKIKNQKTQIKLHLSAKANNAQNIERMKQIEKELKQMELIKDQYQKKNYEQSLSIQRFVCEMTNLQKEMQMLAKSQYDASVRNKQQELHLEAERKIRQELENRCQELEETVRHLKKCKEATENTLKEASVESEQITANLEEAHRWFKHRFDGLQLELTKNRLQRPSGEDRWQEKDQDVKHDVMSNQSVLHRWERKQNLRPMPKKYHSEVQRK |
Proteomic databases
PTM databases
Expression
Interaction
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | Q8NCX0 | GOLGA2 Q08379 | 3 | EBI-10269342, EBI-618309 | |
BINARY | Q8NCX0 | NUP62 P37198 | 3 | EBI-10269342, EBI-347978 | |
BINARY | Q8NCX0-3 | EAF1 Q96JC9 | 3 | EBI-12235840, EBI-769261 | |
BINARY | Q8NCX0-3 | GOLGA2 Q08379 | 3 | EBI-12235840, EBI-618309 | |
BINARY | Q8NCX0-3 | NUTF2 P61970 | 3 | EBI-12235840, EBI-591778 | |
BINARY | Q8NCX0-3 | PRPF18 Q99633 | 3 | EBI-12235840, EBI-2798416 | |
BINARY | Q8NCX0-3 | PSMB5 P28074 | 3 | EBI-12235840, EBI-357828 |
Protein-protein interaction databases
Miscellaneous
Structure
Family & Domains
Features
Showing features for coiled coil, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Coiled coil | 106-299 | |||||
Sequence: RLESLMQSLKMNIFRLQTEKDLNPQKTAFLKDRLNAIQEEHSKDLKLLHLEVMNLRQQLRAVKEEEDKAQDEVQRLTATLKIASQTKKNAAIIEEELKTTKRKMNLKIQELRRQLAQEKYLRESLEKSASAMLLKIQEMGSTVEVERKQVHILQQNCIALRDSIQSAQELLAQEQKKKEELEIATSQLKSDLTS | ||||||
Coiled coil | 398-680 | |||||
Sequence: AAHASITNELQTVQNEKTQLQAHLDHLILEHNQCIQKAQDAEKRTAVQKELLESTIARLRGELEASMQEKKSLLEEKERFQREVNKTEKEIVQERCNLEKELAKNKVDINTLTHNLQTLEEENKHLADQMASLELQQVTSDYHGLAQQKVEKITESKNKLAYENGKLQIKVKQLEEQVQSFTDTSLQNDHLRKMNKYLQTKYAQANSELSAKRVHLQQADAHLKEVKSILERSKEELSRTVKCRNAALKESQKLKEDLEAVEDRENKKVGNFQRQLAEAKEDN | ||||||
Coiled coil | 712-940 | |||||
Sequence: DSEIAGLKKERDLNQQRVQKLEAEVDQWQARMLVMEDQHNSEIESLQKALGVAREDNRKLAMSLEQALQTNNHLQTKLDHIQEQLESKELERQNLETFKDRMTEESKVEAELHAERIEALRKQFQTERETTKKVAQREVAELKKALDEANFRSVEVSRTNRELRQKLAELEKILESNKEKIKNQKTQIKLHLSAKANNAQNIERMKQIEKELKQMELIKDQYQKKNYEQ | ||||||
Coiled coil | 970-1033 | |||||
Sequence: VRNKQQELHLEAERKIRQELENRCQELEETVRHLKKCKEATENTLKEASVESEQITANLEEAHR | ||||||
Region | 1055-1101 | Disordered | ||||
Sequence: SGEDRWQEKDQDVKHDVMSNQSVLHRWERKQNLRPMPKKYHSEVQRK |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence & Isoforms
- Sequence statusComplete
This entry describes 4 isoforms produced by Alternative splicing.
Q8NCX0-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length1,101
- Mass (Da)128,761
- Last updated2008-04-08 v2
- Checksum1D22BFF73725E588
Q8NCX0-2
- Name2
- Differences from canonical
Q8NCX0-3
- Name3
Q8NCX0-4
- Name4
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Sequence caution
Features
Showing features for alternative sequence, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Alternative sequence | VSP_032873 | 1-513 | in isoform 2 | |||
Sequence: Missing | ||||||
Alternative sequence | VSP_032872 | 1-685 | in isoform 3 and isoform 4 | |||
Sequence: Missing | ||||||
Alternative sequence | VSP_032874 | 514-622 | in isoform 2 | |||
Sequence: QTLEEENKHLADQMASLELQQVTSDYHGLAQQKVEKITESKNKLAYENGKLQIKVKQLEEQVQSFTDTSLQNDHLRKMNKYLQTKYAQANSELSAKRVHLQQADAHLKE → MPLRKRKSPERTASSKSPEISRSHVNSIKERTSSVGLPSVIPNSTRRVSFAPNLPSMKTSQDIGDSRISLKTLLNAIKTMEGRLEGKIEILASRPLINDESPNFLKQDS | ||||||
Sequence conflict | 746 | in Ref. 5; AAH62658 | ||||
Sequence: M → V | ||||||
Sequence conflict | 841 | in Ref. 5; AAH62658 | ||||
Sequence: T → A | ||||||
Alternative sequence | VSP_032875 | 853 | in isoform 4 | |||
Sequence: L → V | ||||||
Alternative sequence | VSP_032876 | 854-1101 | in isoform 4 | |||
Sequence: Missing | ||||||
Alternative sequence | VSP_032877 | 918-930 | in isoform 2 and isoform 3 | |||
Sequence: QIEKELKQMELIK → VVWETSSHFLDTL | ||||||
Alternative sequence | VSP_032878 | 931-1101 | in isoform 2 and isoform 3 | |||
Sequence: Missing |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK096130 EMBL· GenBank· DDBJ | BAC04706.1 EMBL· GenBank· DDBJ | mRNA | ||
AL834537 EMBL· GenBank· DDBJ | CAD39193.1 EMBL· GenBank· DDBJ | mRNA | ||
AC068544 EMBL· GenBank· DDBJ | AAY14905.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CH471063 EMBL· GenBank· DDBJ | EAW70131.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BC062449 EMBL· GenBank· DDBJ | AAH62449.1 EMBL· GenBank· DDBJ | mRNA | ||
BC062658 EMBL· GenBank· DDBJ | AAH62658.1 EMBL· GenBank· DDBJ | mRNA | Sequence problems. |