Q8NCJ5 · SPRY3_HUMAN
- ProteinSPRY domain-containing protein 3
- GeneSPRYD3
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids442 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSPRY domain-containing protein 3
Gene names
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Hominoidea (apes) > Hominidae (great apes) > Homininae > Homo
Accessions
- Primary accessionQ8NCJ5
- Secondary accessions
Proteomes
Organism-specific databases
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 357 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000240854 | 1-442 | SPRY domain-containing protein 3 | |||
Sequence: MRRTRRPRFVLMNKMDDLNLHYRFLNWRRRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSGVRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFGSKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGSTIMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSVMMVDSYEDEWGRLHDVRVCGTLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIALGLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVGDPFGPRCYKGDIMGCGIMFPRDYILDSEGDSDDSCDTVILSPTARAVRNVRNVMYLHQEGEEEEEEEEEEEDGEEIEPEHEGRKVVVFFTRNGKIIGKKDAVVPSGGFFPTIGMLSCGEKVKVDLHPLSG |
Proteomic databases
PTM databases
Expression
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 17-204 | B30.2/SPRY | ||||
Sequence: DLNLHYRFLNWRRRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSGVRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFGSKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGSTIMPMSPDGLFPAVGMHSLGEEVRLHLNAELG | ||||||
Compositional bias | 371-388 | Acidic residues | ||||
Sequence: EGEEEEEEEEEEEDGEEI | ||||||
Region | 371-394 | Disordered | ||||
Sequence: EGEEEEEEEEEEEDGEEIEPEHEG |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length442
- Mass (Da)49,694
- Last updated2006-10-17 v2
- ChecksumBB868EF60894E66D
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Features
Showing features for sequence conflict, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 359 | in Ref. 1; BAC11144 | ||||
Sequence: V → I | ||||||
Compositional bias | 371-388 | Acidic residues | ||||
Sequence: EGEEEEEEEEEEEDGEEI |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK027706 EMBL· GenBank· DDBJ | BAB55311.1 EMBL· GenBank· DDBJ | mRNA | ||
AK074694 EMBL· GenBank· DDBJ | BAC11144.1 EMBL· GenBank· DDBJ | mRNA | ||
CH471054 EMBL· GenBank· DDBJ | EAW96662.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BC136312 EMBL· GenBank· DDBJ | AAI36313.1 EMBL· GenBank· DDBJ | mRNA |