Q8NA23 · WDR31_HUMAN
- ProteinWD repeat-containing protein 31
- GeneWDR31
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids367 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameWD repeat-containing protein 31
Gene names
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Hominoidea (apes) > Hominidae (great apes) > Homininae > Homo
Accessions
- Primary accessionQ8NA23
- Secondary accessions
Proteomes
Organism-specific databases
Disease & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | VAR_053426 | 113 | in dbSNP:rs10817479 | |||
Sequence: P → S |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 381 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000051380 | 1-367 | WD repeat-containing protein 31 | |||
Sequence: MLLLRCQLKQAPPQKVSFRFCVVMGKQQSKLKHSTYKYGRPDEIIEERIQTKAFQEYSPAHMDTVSVVAALNSDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFSASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGEGCEATLWDLRQTRNRICEYKGHFQTVASCVFLPRALALMPLIATSSHDCKVKIWNQDTGACLFTLSLDGSGPLTSLAVGDAISLLCASFNRGIHLLRMDHSQGLELQEVAAF |
Proteomic databases
PTM databases
Expression
Interaction
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | Q8NA23-2 | CASP6 P55212 | 3 | EBI-25835937, EBI-718729 | |
BINARY | Q8NA23-2 | COMT P21964-2 | 3 | EBI-25835937, EBI-10200977 | |
BINARY | Q8NA23-2 | HIP1 O00291 | 3 | EBI-25835937, EBI-473886 | |
BINARY | Q8NA23-2 | LAMP2 P13473-2 | 3 | EBI-25835937, EBI-21591415 | |
BINARY | Q8NA23-2 | UBB P0CG47 | 3 | EBI-25835937, EBI-413034 |
Protein-protein interaction databases
Miscellaneous
Structure
Family & Domains
Features
Showing features for repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 53-90 | WD 1 | ||||
Sequence: AFQEYSPAHMDTVSVVAALNSDLCVSGGKDKTVVAYNW | ||||||
Repeat | 94-132 | WD 2 | ||||
Sequence: NVVKRFKGHEHEITKVACIPKSSQFFSASRDRMVMMWDL | ||||||
Repeat | 137-175 | WD 3 | ||||
Sequence: QPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDV | ||||||
Repeat | 179-217 | WD 4 | ||||
Sequence: QSVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWDS | ||||||
Repeat | 221-264 | WD 5 | ||||
Sequence: QVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGEGCEATLWDL | ||||||
Repeat | 269-311 | WD 6 | ||||
Sequence: NRICEYKGHFQTVASCVFLPRALALMPLIATSSHDCKVKIWNQ | ||||||
Repeat | 315-353 | WD 7 | ||||
Sequence: ACLFTLSLDGSGPLTSLAVGDAISLLCASFNRGIHLLRM |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
Q8NA23-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length367
- Mass (Da)40,840
- Last updated2002-10-01 v1
- Checksum57B317C3164749CA
Q8NA23-2
- Name2
- Differences from canonical
- 40-40: Missing
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Features
Showing features for alternative sequence.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Alternative sequence | VSP_010418 | 40 | in isoform 2 | |||
Sequence: Missing |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK093240 EMBL· GenBank· DDBJ | BAC04106.1 EMBL· GenBank· DDBJ | mRNA | ||
AL137066 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AL449305 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CH471090 EMBL· GenBank· DDBJ | EAW87368.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BC012352 EMBL· GenBank· DDBJ | AAH12352.1 EMBL· GenBank· DDBJ | mRNA |