Q8N9H9 · CA127_HUMAN
- ProteinUncharacterized protein C1orf127
- GeneC1orf127
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids656 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUncharacterized protein C1orf127
Gene names
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Hominoidea (apes) > Hominidae (great apes) > Homininae > Homo
Accessions
- Primary accessionQ8N9H9
- Secondary accessions
Proteomes
Organism-specific databases
Disease & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | VAR_056766 | 256 | in dbSNP:rs1281012 | |||
Sequence: R → Q | ||||||
Natural variant | VAR_056767 | 366 | in dbSNP:rs1281016 | |||
Sequence: V → D | ||||||
Natural variant | VAR_031750 | 530 | in dbSNP:rs1281018 | |||
Sequence: A → V |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 3 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000284492 | 1-656 | Uncharacterized protein C1orf127 | |||
Sequence: MKCPMLRSRLGQESVHCGPMFIQVSRPLPLWRDNRQTPWLLSLRGELVASLEDASLMGLYVDMNATTVTVQSPRQGLLQRWEVSGGQQALPGVSFQPESEVLVHIPKQRLGLVKRGSYIEETLSLRFLRVHQSNIFMVTENKDFVVVSIPAAGVLQVQRCQEVGGTPGTQAFYRVDLSLEFAEMAAPVLWTVESFFQCVGSGTESPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLSLWAPTGVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPELQDSVEGLSERPSR |
Proteomic databases
PTM databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 206-242 | Disordered | ||||
Sequence: PASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAG | ||||||
Compositional bias | 216-230 | Pro residues | ||||
Sequence: PSPPSPGPETPPAGV | ||||||
Region | 269-422 | Disordered | ||||
Sequence: FLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQ | ||||||
Compositional bias | 299-316 | Pro residues | ||||
Sequence: PPGEAGIPGHPTPPATLP | ||||||
Region | 434-520 | Disordered | ||||
Sequence: AEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPEL | ||||||
Compositional bias | 497-511 | Polar residues | ||||
Sequence: DATFSTPSVRQPDPS | ||||||
Region | 632-656 | Disordered | ||||
Sequence: ALSAESHRPPELQDSVEGLSERPSR |
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
Q8N9H9-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length656
- Mass (Da)69,787
- Last updated2007-04-17 v2
- Checksum3C2BB4E265669023
Q8N9H9-2
- Name2
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Features
Showing features for alternative sequence, sequence conflict, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Alternative sequence | VSP_024543 | 84-92 | in isoform 2 | |||
Sequence: SGGQQALPG → LNTSAELLPLWLVSGHHAYSLEAACPP | ||||||
Sequence conflict | 127 | in Ref. 1; BAC04355 | ||||
Sequence: F → L | ||||||
Sequence conflict | 205 | in Ref. 1; BAC04355 | ||||
Sequence: S → P | ||||||
Compositional bias | 216-230 | Pro residues | ||||
Sequence: PSPPSPGPETPPAGV | ||||||
Alternative sequence | VSP_024544 | 238-263 | in isoform 2 | |||
Sequence: Missing | ||||||
Compositional bias | 299-316 | Pro residues | ||||
Sequence: PPGEAGIPGHPTPPATLP | ||||||
Compositional bias | 497-511 | Polar residues | ||||
Sequence: DATFSTPSVRQPDPS |
Keywords
- Coding sequence diversity
- Technical term