Q8N8F6 · YIPF7_HUMAN

  • Protein
    Protein YIPF7
  • Gene
    YIPF7
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    4/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum membrane
Cellular Componenttrans-Golgi network
Biological Processendoplasmic reticulum to Golgi vesicle-mediated transport
Biological Processvesicle fusion with Golgi apparatus

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein YIPF7
  • Alternative names
    • Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 9
    • YIP1 family member 7

Gene names

    • Name
      YIPF7
    • Synonyms
      FINGER9, YIP1B

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q8N8F6
  • Secondary accessions
    • J3KR00
    • Q3SY21
    • Q3SY22

Proteomes

Organism-specific databases

Subcellular Location

Endoplasmic reticulum membrane
; Multi-pass membrane protein
Note: Evenly distributed between cis- and trans-Golgi apparatus.

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-125Cytoplasmic
Transmembrane126-146Helical
Topological domain147Extracellular
Transmembrane148-168Helical
Topological domain169-172Cytoplasmic
Transmembrane173-193Helical
Topological domain194-196Extracellular
Transmembrane197-217Helical
Topological domain218-235Cytoplasmic
Transmembrane236-256Helical

Keywords

Disease & Variants

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variantVAR_04303630in dbSNP:rs2348353

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 401 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Organism-specific databases

Miscellaneous

Genetic variation databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003330071-256Protein YIPF7

Proteomic databases

PTM databases

Expression

Gene expression databases

Organism-specific databases

Interaction

Protein-protein interaction databases

Miscellaneous

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region18-48Disordered

Sequence similarities

Belongs to the YIP1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoforms

Align isoforms (5)
  • Sequence status
    Complete

This entry describes 5 isoforms produced by Alternative splicing.

Q8N8F6-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    256
  • Mass (Da)
    27,776
  • Last updated
    2024-01-24 v3
  • Checksum
    90A72594F902C196
MSNLAQFDSDFYQSNFTIDNQEQSGNDSNAYGNLYGSRKQQAGEQPQPASFVPSEMLMSSGYAGQFFQPASNSDYYSQSPYIDSFDEEPPLLEELGIHFDHIWQKTLTVLNPMKPVDGSIMNETDLTGPILFCVALGATLLLAGKVQFGYVYGMSAIGCLVIHALLNLMSSSGVSYGCVASVLGYCLLPMVILSGCAMFFSLQGIFGIMSSLVIIGWCSLSASKIFIAALHMEGQQLLVAYPCAILYGLFALLTIF

Q8N8F6-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical
    • 143-256: AGKVQFGYVYGMSAIGCLVIHALLNLMSSSGVSYGCVASVLGYCLLPMVILSGCAMFFSLQGIFGIMSSLVIIGWCSLSASKIFIAALHMEGQQLLVAYPCAILYGLFALLTIF → VMCHRKHQILMLVLSSAGFEAICINIRETVSPYIVNFLSERE

Q8N8F6-3

  • Name
    3
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical

Q8N8F6-4

  • Name
    4
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical
    • 94-108: ELGIHFDHIWQKTLT → DKNLESILITYGKKL
    • 109-256: Missing

Q8N8F6-5

  • Name
    5
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical
    • 39-39: K → KLNRKHGDSCSWGGHRELLLMVEGTGASSHRAGAGSRER
    • 123-256: Missing

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
V9GZ30V9GZ30_HUMANYIPF739
A0A804HK52A0A804HK52_HUMANYIPF764
A0A804HL09A0A804HL09_HUMANYIPF762

Sequence caution

The sequence AAI03996.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.
The sequence AAI03997.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.
The sequence BAC04887.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.

Features

Showing features for sequence conflict, alternative sequence.

TypeIDPosition(s)Description
Sequence conflict26in Ref. 1; BAC04887
Alternative sequenceVSP_06219439in isoform 5
Alternative sequenceVSP_03343140-44in isoform 3
Alternative sequenceVSP_03343245-256in isoform 3
Alternative sequenceVSP_03343394-108in isoform 4
Alternative sequenceVSP_033434109-256in isoform 4
Sequence conflict114in Ref. 1; BAC04887
Alternative sequenceVSP_062195123-256in isoform 5
Alternative sequenceVSP_033435143-256in isoform 2

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DA899652
EMBL· GenBank· DDBJ
-mRNA No translation available.
AK096895
EMBL· GenBank· DDBJ
BAC04887.1
EMBL· GenBank· DDBJ
mRNA Different initiation
AC093852
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC096586
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC108478
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BC103995
EMBL· GenBank· DDBJ
AAI03996.1
EMBL· GenBank· DDBJ
mRNA Different initiation
BC103996
EMBL· GenBank· DDBJ
AAI03997.1
EMBL· GenBank· DDBJ
mRNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp