Q8MZR8 · Q8MZR8_ENTHI

  • Protein
    Putative trypanothione reductase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionglutathione-disulfide reductase (NADPH) activity
Biological Processcell redox homeostasis
Biological Processcellular response to oxidative stress
Biological Processglutathione metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • Putative trypanothione reductase

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • HK9
  • Taxonomic lineage
    Eukaryota > Amoebozoa > Evosea > Archamoebae > Mastigamoebida > Entamoebidae > Entamoeba

Accessions

  • Primary accession
    Q8MZR8

Subcellular Location

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-282FAD/NAD(P)-binding
Domain305-394Pyridine nucleotide-disulphide oxidoreductase dimerisation

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    394
  • Mass (Da)
    43,558
  • Last updated
    2002-10-01 v1
  • MD5 Checksum
    AABF1B84252B7B488E95BCE92E4CDD54
CVNVGCVPGKYLLFQYLSYNRESALMGYEFDRSSFRAEVQNLIALLSVAVLNINKSYDEMFRETRGVKRLGAPILNVKNTVHVRESADVASLVLFRLETLFIFLASGSFPHMLNIPGLEECISSDESFELPDPPRRVLVVGGGYISVEFAGIFNAYKPEGGNVTLCYRNELILRGFDLTLREELTKELTANGIQSYTKDFPNKVSLNTDGSESVFESGRKMDYDCIFMAIGRIPFTKDLQLNNAQVLIDKGLIQVDEFSTTIANIEAIGDLTTSLELTPVAINFRALVHTVFGSTPRKTDLSVHSSVFSIPNIGLVGLISEVAHKRFKVVAVYESSFRNLKTNITGSKYSTNHSFIRILGVHNLGLGAPEIIQGINVKLNAKIADFLTIGVHPT

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue394

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF503571
EMBL· GenBank· DDBJ
AAM28598.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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