Q8MX40 · IDGF1_DROYA

Function

function

Cooperates with insulin-like peptides to stimulate the proliferation, polarization and motility of imaginal disk cells. May act by stabilizing the binding of insulin-like peptides to its receptor through a simultaneous interaction with both molecules to form a multiprotein signaling complex (By similarity).

Miscellaneous

Lacks the typical Glu active site in position 150 that is replaced by a Gln residue, preventing the hydrolase activity. Its precise function remains unclear.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular region
Molecular Functionchitin binding
Molecular Functionimaginal disc growth factor receptor binding
Biological Processcarbohydrate metabolic process
Biological Processchitin-based cuticle development
Biological Processecdysis, chitin-based cuticle
Biological Processepithelium regeneration
Biological Processimaginal disc development
Biological Processregulation of stem cell division
Biological Processwound healing

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Chitinase-like protein Idgf1
  • Alternative names
    • Imaginal disk growth factor protein 1

Gene names

    • Name
      Idgf1

Organism names

  • Taxonomic identifier
  • Strain
    • #14021-0261.0
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q8MX40

Subcellular Location

Secreted
Note: Secreted in hemolymph. It is probably transported to target tissues via hemolymph.

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, glycosylation.

TypeIDPosition(s)Description
Signal1-20
ChainPRO_000001198221-439Chitinase-like protein Idgf1
Disulfide bond26↔53
Glycosylation122N-linked (GlcNAc...) asparagine
Glycosylation218N-linked (GlcNAc...) asparagine
Disulfide bond340↔423
Glycosylation346N-linked (GlcNAc...) asparagine

Post-translational modification

Glycosylated.

Keywords

PTM databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain22-439GH18

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    439
  • Mass (Da)
    49,244
  • Last updated
    2002-10-01 v1
  • Checksum
    EDE16BFD82A18B9E
MRFQLCYLLGLLSVTSLSHAASNLICYYDSTSYLRQGLAKMHTHELDLALQFCTHLVYGYAGLKAGTLELFSLNVDLDMFYYKEITALRQKFPQLKILLSVGGDRDVDEAHPNKYVELLEANRTFQQNFIDSSMILVKRNGFDGLDLAFQLPRNKPRKVHGSLGTYWKSFKKLFTGDFVVDPLAEQHKSQFTDLVGNLKNAFRSANLMLSLTVLPNVNSTWYFDVPKLHPQFEYINLAAFDFLTPVRNPEEADFTAPIFFQDEQNRLPHLNVEFQVNYWLQNNCPGQKLNLGIASYGRAWKLSKGSGLSGAPIVQETCGAAPGGIQIQSADGLLSWPEICSKLSQNASAQYRGEMAPLRKVTDLTQKYGNYALRPADDNGDFGVWLSFDDPDFAGIKAAYAKGKGLGGVAIFDLSYDDFRGLCTGQKFPIVRSIKYFMG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF394712
EMBL· GenBank· DDBJ
AAM69644.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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