Q8MT08 · DRC4_DROME

Function

function

Cytoskeletal linker which probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentGolgi apparatus
Cellular Componentmicrotubule
Cellular Componentmotile cilium
Molecular Functionmicrotubule binding
Molecular Functionsmall GTPase binding
Biological Processflagellated sperm motility

Names & Taxonomy

Protein names

  • Recommended name
    Dynein regulatory complex subunit 4
  • Alternative names
    • Growth arrest-specific protein 8

Gene names

    • Name
      Gas8
    • ORF names
      CG14271

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q8MT08
  • Secondary accessions
    • Q8T9R5
    • Q9W4R6

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002203801-479Dynein regulatory complex subunit 4

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for coiled coil.

TypeIDPosition(s)Description
Coiled coil28-93
Coiled coil117-170
Coiled coil210-347

Sequence similarities

Belongs to the DRC4 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    479
  • Mass (Da)
    57,168
  • Last updated
    2002-10-01 v1
  • MD5 Checksum
    80638C67C222D0B43A30448B1FDEC0C3
MPPKGKKGKKGKKLPVLIDGVDTSAMTRDQLEAFALRLKAEMDREREERNYFQLERDKIRTFWEITRQQLDETRYELQQKDKEIEATQDLADIDTKHVMQQMKHLQFENHNRLGEVRAEAMTQLKLAQEHHVLQENELQRDKRQLRRMLRERMEMSEMQLRQMEAHFNEKLLEQRITFERERKDNEMLHEEKMIEQKAKLDLFYGTQMFEVEERKNQQIKDLQDHHDLAFNDMKNYYNDITLNNLALIGSMKEQLEHLRKQAERSDRIAADTAAENRRLKEPLEHANIQLNEYRRKLEFYERDKQQLSRLKTRNTRLEKKVKGLTWEAETLILRNDSLVAEREGLKERFNDVIVELQQKTGLKNVLLERKIAALMREDEKRSIVLHETIATCAPNFAEKLTSLDERVGNIIDEKNKIILDLRYEVTKARKAHDDLLETYECKLKQYGVPTDELGFKPIRNRDQQQLYVCGPAGIITENK

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
X2JI73X2JI73_DROMEGas8479
X2JCG2X2JCG2_DROMEGas8454

Sequence caution

The sequence AAL79828.1 differs from that shown. Reason: Erroneous initiation

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF468957
EMBL· GenBank· DDBJ
AAL79828.1
EMBL· GenBank· DDBJ
mRNA Different initiation
AE014298
EMBL· GenBank· DDBJ
AAF45877.3
EMBL· GenBank· DDBJ
Genomic DNA
AY118453
EMBL· GenBank· DDBJ
AAM49822.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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