Q8MRS4 · Q8MRS4_DROME
- ProteinMethionine--tRNA ligase, cytoplasmic
- GeneMetRS
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1012 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | aminoacyl-tRNA synthetase multienzyme complex | |
Cellular Component | cytoplasm | |
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | methionine-tRNA ligase activity | |
Biological Process | methionyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethionine--tRNA ligase, cytoplasmic
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ8MRS4
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 66-179 | GST C-terminal | |||
Domain | 814-870 | WHEP-TRS | |||
Region | 861-885 | Disordered | |||
Compositional bias | 870-885 | Polar residues | |||
Domain | 881-937 | WHEP-TRS | |||
Domain | 952-1007 | WHEP-TRS | |||
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,012
- Mass (Da)111,463
- Last updated2002-10-01 v1
- MD5 Checksum1D5DE01D9AF6F74B0A092B16CAFF3EAF
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 870-885 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY119445 EMBL· GenBank· DDBJ | AAM50099.1 EMBL· GenBank· DDBJ | mRNA |