Q8MRN5 · Q8MRN5_DROME

Function

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site, site.

1952100200300400500600700800900
TypeIDPosition(s)Description
Binding site355Zn2+ (UniProtKB | ChEBI); catalytic
Active site356Proton acceptor
Binding site359Zn2+ (UniProtKB | ChEBI); catalytic
Binding site378Zn2+ (UniProtKB | ChEBI); catalytic
Site441Transition state stabilizer

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentextracellular space
Cellular Componentmembrane
Cellular Componentplasma membrane
Cellular Componentside of membrane
Molecular Functionmetalloaminopeptidase activity
Molecular Functionpeptide binding
Molecular Functionzinc ion binding
Biological Processpeptide catabolic process
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Aminopeptidase
  • EC number

Gene names

    • Name
      CG5839
    • Synonyms
      anon-WO0140519.125
      , anon-WO0140519.65
      , Dmel\CG31233
    • ORF names
      CG31233
      , Dmel_CG31233

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q8MRN5
  • Secondary accessions
    • Q9VD86

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Lipid-anchor, GPI-anchor
Membrane
; Lipid-anchor, GPI-anchor

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-24
ChainPRO_501509931625-952Aminopeptidase

Keywords

Proteomic databases

Expression

Gene expression databases

    • FBgn0051233Expressed in adult midgut (Drosophila) and 20 other cell types or tissues

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain64-249Aminopeptidase N-like N-terminal
Domain295-507Peptidase M1 membrane alanine aminopeptidase
Domain586-904ERAP1-like C-terminal

Sequence similarities

Belongs to the peptidase M1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    952
  • Mass (Da)
    106,858
  • Last updated
    2002-10-01 v1
  • Checksum
    A42AB7D83C78812C
MSCVQVGGMSVFLVLLLAISATQAAVVRQYPILDHLQHLENPMQRLVVPLADEDNYRLPYDTIPSHYAVSLSTNVHTGDTVFNGTVAITLSVLNTTTKIVVHARQLENFTASIIQQGVTEAVAQELVYEYEAEREFLTFSKTGLTFPEDTTWILTINYQGHLRTDNGGFYLSTYTDEEGNTKYLATTQFESTDARHAFPCYDEPSKRAEFTITIKHDPSYNAISNMPVDSSSTSGVTVFQKTVNMPSYLVAFIVSEFVFSEGELNGLPQRVFSRNGTEHEQEWALTTGMLVEKRLSGYFDVPFALPKLDQAGIPDFAAGAMENWGLATYREEYLLYNTENSTTSTQTNIATIEAHEDAHMWFGDLVAIEWWSFLWLKEGFATLFENLAVDLAYPEWDIFQTFHAGSYQSALVNDASANARPMSHFVQKPSEIALLYDSVSYAKAGSVLDMWRHALTNTVFQRGLHNYLVDNQFTAANPSKLFEAIAKAAVEENYEVKATVPDMMGSWTNQGGVPLLTVTRNYDNGSFTVKQSVYTNDKDYTNDKLWYVPINYAESKNPDFRNTEATHYLLNQSEITIYSDLDQTNWLILNKKSTGYYRVLYDAQNYQLITSALITRPHKIDPRNRAQLINDLYRFATSGRVPHATLLELLTYLPQEDQYSPWSATNTVITLLNRYLSGDADYGNFQFYVRELVSLQFDKFGVNDNKGDHHLVPFTRNVLINLACLAGLENCLTETTAKLTALVEEGTKIEPNLQSQVYCNGLKQADDKTFDFVFNKLLNSTDQAERRLLISALGCSQNTAQLEKFVYSSIEPEGLRDQERITVLSPVYSRGEVGLLVAIEFLQKNWEKYGQLNSGFGGVNPLYSDIVGISAYTVNDKQKDALQELVDTVKGSEYVPSTLQDSVDSNVNANYAWLASNRDPLMTWVAGFRSGSSALNASILAILACLLAAKLF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014297
EMBL· GenBank· DDBJ
AAF55912.3
EMBL· GenBank· DDBJ
Genomic DNA
AY119508
EMBL· GenBank· DDBJ
AAM50162.1
EMBL· GenBank· DDBJ
mRNA
AE014297
EMBL· GenBank· DDBJ
ALI30623.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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