Q8MRL5 · Q8MRL5_DROME

  • Protein
    ADAM metallopeptidase with thrombospondin type 1 motif B, isoform C
  • Gene
    AdamTS-B
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

1769100200300400500600700
Type
IDPosition(s)Description
Binding site316Ca2+ 2 (UniProtKB | ChEBI)
Binding site316Ca2+ 1 (UniProtKB | ChEBI)
Binding site407Ca2+ 1 (UniProtKB | ChEBI)
Binding site456Zn2+ (UniProtKB | ChEBI); catalytic
Active site457
Binding site460Zn2+ (UniProtKB | ChEBI); catalytic
Binding site466Zn2+ (UniProtKB | ChEBI); catalytic
Binding site516Ca2+ 1 (UniProtKB | ChEBI)
Binding site519Ca2+ 2 (UniProtKB | ChEBI)
Binding site519Ca2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentextracellular matrix
Cellular Componentextracellular region
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Biological Processextracellular matrix organization
Biological Processproteolysis

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Submitted names
    • ADAM metallopeptidase with thrombospondin type 1 motif B, isoform C
      (EC:3.4.24.-
      )
    • GH22104p

Gene names

    • Name
      AdamTS-B
    • Synonyms
      CT13580
      , Dmel\CG4096
    • ORF names
      CG4096
      , Dmel_CG4096

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q8MRL5

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-27
ChainPRO_501509931328-769
Disulfide bond389↔440
Disulfide bond418↔422
Disulfide bond434↔516
Disulfide bond473↔500
Disulfide bond544↔571
Disulfide bond566↔596
Disulfide bond590↔601
Disulfide bond623↔660
Disulfide bond627↔665
Disulfide bond638↔650

Keywords

Expression

Gene expression databases

    • FBgn0029791Expressed in compound eye cone cell in insect head and 100 other cell types or tissues

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region181-232Disordered
Compositional bias201-215Basic residues
Region255-276Disordered
Domain313-521Peptidase M12B

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    769
  • Mass (Da)
    86,943
  • Last updated
    2002-10-01 v1
  • Checksum
    39404FBD271E1968
MTCSRMWIRSRWLGLLLHYWLVVVTQGGGVRPLYGLHSDELVAGEGQLVVPRRVHPDGAFMTHQLEYAHELDHRRHRQRRSLNSEHDTQAADLHLLLPLANETLHLELMAHSYFLAPNLVVERHRRDLRTRSPLTTRHLNCHFHGKVRGQPATNVAISTCAGLVGHIRTAGNEYFIEPSKEHEPHPVNGHPHVVFQRSSVKPKHSLRKRNKRKRGGKSGSGAEVSNCGTREPRRRMETRLEWQARGKVKVQGGRQIRRHHHHHHHHHHKHKYRHHQQKISRVPHTKFKYETQFQTEPDHAEIPRRRRSISSPRHVETLIVADATMSAFHRDLNGYLLTIMNMVSALYKDPSIGNSIEIVVVRIIQLDEEESQLQLNLTQNAQKNLDRFCSWQHKLNKGSEKDPHHHDVAILITRKNICANNCMTLGLANVGGMCKPKQSCSVNEDNGIMLSHTITHELGHNFGMFHDTAKIGCHPRVGPIVHIMTPTFGADTLQVCWSNCSRKYITHFLDQGLGECLDDPPTPLDEYNYTGELPGMRYNARGQCRLQFNLTTDSEVGACSAPHEFCSTLWCKVNGECVTHMRPTAPGTLCGRNKWCQNGKCVRREELAAVNGGWGDWSEWSECSRSCGGGVSTQQRECDNPVPANGGVFCIGERKRYKICRKRPCPAEEPSFRAQQCARFDNVSYQGATYKWLPFFDKNNPCKLFCSDVDDTIIANWGATVLDGTPCTLGTNNMCIDGICKLVAIGSSTRRCRTIGAVSAAVLAISASR

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
Q9W493Q9W493_DROMEAdamTS-B1023

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias201-215Basic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY119538
EMBL· GenBank· DDBJ
AAM50192.1
EMBL· GenBank· DDBJ
mRNA
AE014298
EMBL· GenBank· DDBJ
ACZ95215.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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