Q8MRL5 · Q8MRL5_DROME
- ProteinADAM metallopeptidase with thrombospondin type 1 motif B, isoform C
- GeneAdamTS-B
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids769 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 316 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 316 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 407 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 456 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 457 | ||||
Binding site | 460 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 466 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 516 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 519 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 519 | Ca2+ 1 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular matrix | |
Cellular Component | extracellular region | |
Molecular Function | metal ion binding | |
Molecular Function | metalloendopeptidase activity | |
Biological Process | extracellular matrix organization | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Protein family/group databases
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ8MRL5
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-27 | ||||
Chain | PRO_5015099313 | 28-769 | |||
Disulfide bond | 389↔440 | ||||
Disulfide bond | 418↔422 | ||||
Disulfide bond | 434↔516 | ||||
Disulfide bond | 473↔500 | ||||
Disulfide bond | 544↔571 | ||||
Disulfide bond | 566↔596 | ||||
Disulfide bond | 590↔601 | ||||
Disulfide bond | 623↔660 | ||||
Disulfide bond | 627↔665 | ||||
Disulfide bond | 638↔650 | ||||
Keywords
- PTM
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 181-232 | Disordered | |||
Compositional bias | 201-215 | Basic residues | |||
Region | 255-276 | Disordered | |||
Domain | 313-521 | Peptidase M12B | |||
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length769
- Mass (Da)86,943
- Last updated2002-10-01 v1
- Checksum39404FBD271E1968
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q9W493 | Q9W493_DROME | AdamTS-B | 1023 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 201-215 | Basic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY119538 EMBL· GenBank· DDBJ | AAM50192.1 EMBL· GenBank· DDBJ | mRNA | ||
AE014298 EMBL· GenBank· DDBJ | ACZ95215.1 EMBL· GenBank· DDBJ | Genomic DNA |