Q8MKD8 · Q8MKD8_FELCA

Function

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentnuclear envelope
Cellular Componentperinuclear region of cytoplasm
Cellular Componentplasma membrane
Molecular Functionlipid transporter activity
Biological Processbile acid metabolic process
Biological Processcholesterol homeostasis
Biological Processcholesterol transport
Biological Processlysosomal transport

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Niemann-Pick C1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Feliformia > Felidae > Felinae > Felis

Accessions

  • Primary accession
    Q8MKD8

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane267-293Helical
Transmembrane353-371Helical
Transmembrane621-642Helical
Transmembrane654-678Helical
Transmembrane684-706Helical
Transmembrane727-748Helical
Transmembrane760-785Helical
Transmembrane1097-1115Helical
Transmembrane1122-1143Helical
Transmembrane1149-1167Helical
Transmembrane1188-1214Helical
Transmembrane1226-1249Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-22
ChainPRO_500431134123-1276

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain620-785SSD

Sequence similarities

Belongs to the patched family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,276
  • Mass (Da)
    141,711
  • Last updated
    2002-10-01 v1
  • Checksum
    C2DD3496472B71EF
MTARGPALGLLLLLLCPAQVLAQSCIWYGECGIASGDKRYNCKYSGPPKPLPKDGYDLVQELCPGFFFDNVSLCCDVQQLQTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKTNVKELQYYIGESFANAMYNACRDVEAPSSNDKALGLLCGKDAEACNATNWIEYMFSKDNGQAPFTITPIFSDLPTHGMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQPPPPPVPWRILGLDAMYVIMWITYMAFLLVFFGAFFALWCYRKRYFVSEYTPIDSNIAFSVNANDRGEASCCDALGAAFEGCLRRLFSQWGSFCVRNPGPIIFFSLAFIAACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTSAHTYQPYPSGSDVPFGPPLDLAILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSVLNYFQNSHSMLDHEIGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTERLQKAHVWEKEFINFVKNYKNPNLTISFTTERSIEDELNRESNGDIFTVIISYAIMFLYISIALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYVGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLHGETLDQQLGRVLGEVAPSMFLSSFSEAVAFFLGALSKMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVLCCVRGSEDGTSVQASESCLFRLFKHSYSPLLLKDWMRPIVIAIFVGVLSFSVAVLNKVEIGLDQSLSMPDDSYVMDYFKSLKYLHAGPPVYFVLEEGHDYTSLKGQNMVCGGMGCNNDSLVQQIFNAAQLDSYTRIGFAPSSWIDDYFDWVKPQSSCCRVYNSTDRFCNASVVDPACIRCRPLTQEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILGNDTGVGATYFMTYHTVLQTSADFTDAMRKANLIASNITKTMGLEGSNYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGAIFLVTVILLGCDLWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRAQRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSINKAKSLATQEQYKGTEREQLLNF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF503634
EMBL· GenBank· DDBJ
AAM27451.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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