Q8LJT8 · TKI1_ARATH
- ProteinTSL-kinase interacting protein 1
- GeneTKI1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids743 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | chromatin binding | |
Molecular Function | DNA binding | |
Biological Process | pattern specification process |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameTSL-kinase interacting protein 1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ8LJT8
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000270796 | 1-743 | TSL-kinase interacting protein 1 | |||
Sequence: MLKQFTHYCEMQAELIPEGPNGEGRLSNQNSNPNLLSSASISITQFPAKKPTRQWAAWTHQEEESFFTALRQVGKNFEKITSRVQSKNKDQVRHYYYRLVRRMNKLLGPDLSLDAKNPKDTNAAMLRWWSLLEKYSCKASKLHLKPRRFKLFIEALEHQLLKDRRKSIRKRTCQGENLSSASLGNISSHSRERGLDNRPFKLILSDGQNVKKLGPGRASTKHGESLSVNLGDEKEDTAFGRGGRQRRKQGYRKWEKAAIDGVSLVADAAEHLERTSIDKDMDDQTDLGPTRYLTGKSPLSLCSAGDVPLSDANMQFSAKLKLQLFPIDECTRRSLEMDKHNPHLELTLSNRKKISSVLEHLNRKWGSSSCATGELLLFPYNARKETVTCHQRWTHDSFLSAAEVHSMVGSPSVFRLRYGWFVHDASGSIISQVPTSDPCPSLEDDMNVDRLNEVNMLLTESGPLSVHSTAEQTTSVEPSQGLVCASGVHDRPARSRDDYEPASTSITPLEHLSGGNAQSPGEWADSLTNISIGDLLSEVPDDIDSDGVDPPATEGSHYLLRDVPFTSDSFDAAIAAHILRHQNKPSAQLPLTSGSSSLWDDEETRDAFSFQKNRFANSTELASVASPKGVGRVNGEPSQLVEASSGDEGSYNPHDDGDPMEEGPADPHTMDSPGKTPCGLADVYWPDSLGPLDLDIRSSKYTDDLILSESLGGLSRLIATSLDAFQNCSLFGFDNKKDKSNMV |
Post-translational modification
Phosphorylated in vitro by TOUSLED.
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Interaction
Subunit
Interacts only with active kinase forms of TOUSLED. Interacts with SNL1.
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | Q8LJT8 | TOUSLED Q39238 | 4 | EBI-2366507, EBI-2325484 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 53-104 | SANT | ||||
Sequence: RQWAAWTHQEEESFFTALRQVGKNFEKITSRVQSKNKDQVRHYYYRLVRRMN | ||||||
Region | 486-523 | Disordered | ||||
Sequence: SGVHDRPARSRDDYEPASTSITPLEHLSGGNAQSPGEW | ||||||
Compositional bias | 500-523 | Polar residues | ||||
Sequence: EPASTSITPLEHLSGGNAQSPGEW | ||||||
Region | 626-679 | Disordered | ||||
Sequence: SPKGVGRVNGEPSQLVEASSGDEGSYNPHDDGDPMEEGPADPHTMDSPGKTPCG | ||||||
Compositional bias | 649-665 | Basic and acidic residues | ||||
Sequence: GSYNPHDDGDPMEEGPA |
Domain
The Myb domain is not required for TOUSLED binding.
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
Q8LJT8-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length743
- Mass (Da)82,258
- Last updated2007-01-09 v2
- ChecksumB952325D7102ECCC
Q8LJT8-2
- Name2
- NoteMay be due to a competing acceptor splice site.
- Differences from canonical
- 286-287: Missing
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
F4IP39 | F4IP39_ARATH | TKI1 | 744 |
Sequence caution
Features
Showing features for sequence conflict, alternative sequence, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 2 | in Ref. 1; AAM94622 | ||||
Sequence: L → V | ||||||
Alternative sequence | VSP_022229 | 286-287 | in isoform 2 | |||
Sequence: Missing | ||||||
Compositional bias | 500-523 | Polar residues | ||||
Sequence: EPASTSITPLEHLSGGNAQSPGEW | ||||||
Compositional bias | 649-665 | Basic and acidic residues | ||||
Sequence: GSYNPHDDGDPMEEGPA |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF530160 EMBL· GenBank· DDBJ | AAM94622.1 EMBL· GenBank· DDBJ | mRNA | ||
AC006922 EMBL· GenBank· DDBJ | AAD31581.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002685 EMBL· GenBank· DDBJ | AEC09326.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC09327.2 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY064068 EMBL· GenBank· DDBJ | AAL36424.1 EMBL· GenBank· DDBJ | mRNA | ||
AY096376 EMBL· GenBank· DDBJ | AAM20017.1 EMBL· GenBank· DDBJ | mRNA |