Q8LF21 · DRP1C_ARATH

Function

function

Microtubule-associated force-producing protein that is targeted to the growing edges of the cell plate during cytokinesis. Also plays a major role in plasma membrane maintenance during pollen maturation (PubMed:18344418).
Has a GTPase activity (By similarity).

Catalytic activity

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site45-50GTP (UniProtKB | ChEBI)
Binding site213-218GTP (UniProtKB | ChEBI)
Binding site243-246GTP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell cortex
Cellular Componentcell plate
Cellular Componentclathrin-coated vesicle
Cellular Componentcytoplasm
Cellular Componentextracellular region
Cellular Componentmicrotubule
Cellular Componentphragmoplast
Cellular Componentplasma membrane
Cellular Componentplasmodesma
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Biological Processcell division
Biological Processmitochondrial fission
Biological Processmitochondrion organization
Biological Processpollen maturation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phragmoplastin DRP1C
  • EC number
  • Alternative names
    • Dynamin-like protein 1C
    • Dynamin-like protein 5
    • Dynamin-like protein DLP1
    • Dynamin-related protein 1C
      (AtDRP1C
      )

Gene names

    • Name
      DRP1C
    • Synonyms
      ADL1C
      , ADL5
      , DLP1
    • ORF names
      F10B6.23
    • Ordered locus names
      At1g14830

Organism names

  • Taxonomic identifier
  • Strains
    • cv. Landsberg erecta
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8LF21
  • Secondary accessions
    • Q8S3C8
    • Q9FNX6
    • Q9LQU8
    • Q9SE81

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Cytoplasm
Note: Microtubule-associated and localized in the forming cell plate during cytokinesis (PubMed:14750520).
Forms dynamic foci in the cell cortex, which colocalize with part of the clathrin endocytic machinery (PubMed:18344418).

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002065791-614Phragmoplastin DRP1C

Proteomic databases

PTM databases

Expression

Tissue specificity

Ubiquitous.

Gene expression databases

Interaction

Subunit

Forms homodimer and may homooligomerize and heterooligomerize to form the phragmoplastin complex (PubMed:14750520).
Binds to PHIP1 (PubMed:18621982).

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain32-301Dynamin-type G
Region42-49G1 motif
Region68-70G2 motif
Region143-146G3 motif
Region212-215G4 motif
Region242-245G5 motif
Region499-519Disordered
Domain523-614GED

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    614
  • Mass (Da)
    68,723
  • Last updated
    2005-02-01 v2
  • Checksum
    3671AE59885A6C97
MATMKSLIGLINKIQRACTVLGDHGGEGMSLWEALPTVAVVGGQSSGKSSVLESVVGRDFLPRGSGIVTRRPLVLQLHKTEDGTTEYAEFLHAPKKRFADFAAVRKEIEDETDRITGKSKQISNIPIQLSIYSPNVVNLTLIDLPGLTKVAVDGQPESIVQDIENMVRSYVEKPNCIILAISPANQDIATSDAIKLAREVDPTGERTFGVATKLDIMDKGTDCLDVLEGRSYRLQHPWVGIVNRSQADINKRVDMIAARRKEQEYFETSPEYGHLASRMGSEYLAKLLSQHLETVIRQKIPSIVALINKSIDEINAELDRIGRPIAVDSGAQLYTILELCRAFDRVFKEHLDGGRPGGDRIYGVFDHQLPAALKKLPFDRHLSTKNVQKVVSEADGYQPHLIAPEQGYRRLIDGSISYFKGPAEATVDAVHFVLKELVRKSISETEELKRFPTLASDIAAAANEALERFRDESRKTVLRLVDMESSYLTVEFFRKLHLEPEKEKPNPRNAPAPNADPYSDNHFRKIGSNVSAYINMVCDTLRNSLPKAVVYCQVREAKRSLLNFFYAQVGRKEKEKLGAMLDEDPQLMERRGTLAKRLELYKQARDDIDAVAWK

Sequence caution

The sequence AAF79238.1 differs from that shown. Reason: Erroneous gene model prediction
The sequence AAL92170.1 differs from that shown. Reason: Erroneous initiation Truncated N-terminus.

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict23in Ref. 1; AAL92170 and 2; AAF22293

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF488808
EMBL· GenBank· DDBJ
AAL92170.1
EMBL· GenBank· DDBJ
mRNA Different initiation
AF180734
EMBL· GenBank· DDBJ
AAF22293.1
EMBL· GenBank· DDBJ
mRNA
AJ304841
EMBL· GenBank· DDBJ
CAC19656.1
EMBL· GenBank· DDBJ
mRNA
AC006917
EMBL· GenBank· DDBJ
AAF79238.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002684
EMBL· GenBank· DDBJ
AEE29232.1
EMBL· GenBank· DDBJ
Genomic DNA
AY039955
EMBL· GenBank· DDBJ
AAK64059.1
EMBL· GenBank· DDBJ
mRNA
AY150494
EMBL· GenBank· DDBJ
AAN12911.1
EMBL· GenBank· DDBJ
mRNA
AY085091
EMBL· GenBank· DDBJ
AAM61645.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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