Q8LEC0 · RLPHL_ARATH
- ProteinTyrosine-protein phosphatase At3g09960
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids311 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Variants
Variant ID(s) | Position(s) | Change | Description | Clinical significance | Provenance | ||
---|---|---|---|---|---|---|---|
ENSVATH10574481 | 17 | G>V | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 3:g.3062039G>T Codon: GGA/GTA Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062039G>T Locations: - p.Gly17Val (EnsemblPlants:AT3G09960.1) - c.50G>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH10574482 | 18 | N>H | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.64) Somatic: No Accession: 3:g.3062041A>C Codon: AAC/CAC Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062041A>C Locations: - p.Asn18His (EnsemblPlants:AT3G09960.1) - c.52A>C (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH05800892 | 35 | N>I | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.18) Somatic: No Accession: 3:g.3062093A>T Codon: AAC/ATC Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062093A>T Locations: - p.Asn35Ile (EnsemblPlants:AT3G09960.1) - c.104A>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH02127224 | 68 | E>D | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.51) Somatic: No Accession: 3:g.3062193G>T Codon: GAG/GAT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062193G>T Locations: - p.Glu68Asp (EnsemblPlants:AT3G09960.1) - c.204G>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3062198_A_G | 70 | H>R | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.39) Somatic: No Accession: 3:g.3062198A>G Codon: CAT/CGT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062198A>G Locations: - p.His70Arg (EnsemblPlants:AT3G09960.1) - c.209A>G (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH00314294 | 74 | T>A | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.36) Somatic: No Accession: 3:g.3062209A>G Codon: ACC/GCC Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062209A>G Locations: - p.Thr74Ala (EnsemblPlants:AT3G09960.1) - c.220A>G (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3062212_C_T | 75 | H>Y | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: 3:g.3062212C>T Codon: CAT/TAT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062212C>T Locations: - p.His75Tyr (EnsemblPlants:AT3G09960.1) - c.223C>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3062276_C_T | 96 | P>L | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.06) Somatic: No Accession: 3:g.3062276C>T Codon: CCT/CTT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062276C>T Locations: - p.Pro96Leu (EnsemblPlants:AT3G09960.1) - c.287C>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3062282_A_T | 98 | D>V | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.1) Somatic: No Accession: 3:g.3062282A>T Codon: GAT/GTT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062282A>T Locations: - p.Asp98Val (EnsemblPlants:AT3G09960.1) - c.293A>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH10574484 | 99 | G>W | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 3:g.3062284G>T Codon: GGG/TGG Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062284G>T Locations: - p.Gly99Trp (EnsemblPlants:AT3G09960.1) - c.295G>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3062322_A_C | 111 | K>N | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.5) Somatic: No Accession: 3:g.3062322A>C Codon: AAA/AAC Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062322A>C Locations: - p.Lys111Asn (EnsemblPlants:AT3G09960.1) - c.333A>C (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3062343_G_A | 118 | W>* | 1000Genomes | ||||
Consequence: stop gained Somatic: No Accession: 3:g.3062343G>A Codon: TGG/TGA Consequence type: stop gained Cytogenetic band: Genomic location: 3:g.3062343G>A Locations: - p.Trp118Ter (EnsemblPlants:AT3G09960.1) - c.354G>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH05800897 | 120 | K>R | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.32) Somatic: No Accession: 3:g.3062348A>G Codon: AAA/AGA Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062348A>G Locations: - p.Lys120Arg (EnsemblPlants:AT3G09960.1) - c.359A>G (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3062371_C_A | 128 | H>N | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: 3:g.3062371C>A Codon: CAT/AAT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062371C>A Locations: - p.His128Asn (EnsemblPlants:AT3G09960.1) - c.382C>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH00314295 | 130 | Q>K | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.02) Somatic: No Accession: 3:g.3062377C>A Codon: CAA/AAA Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062377C>A Locations: - p.Gln130Lys (EnsemblPlants:AT3G09960.1) - c.388C>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3062384_G_A | 132 | R>K | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 3:g.3062384G>A Codon: AGG/AAG Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062384G>A Locations: - p.Arg132Lys (EnsemblPlants:AT3G09960.1) - c.395G>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH00314296 | 157 | D>N | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.03) Somatic: No Accession: 3:g.3062458G>A Codon: GAT/AAT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062458G>A Locations: - p.Asp157Asn (EnsemblPlants:AT3G09960.1) - c.469G>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3062483_A_T | 165 | Y>F | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.06) Somatic: No Accession: 3:g.3062483A>T Codon: TAT/TTT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062483A>T Locations: - p.Tyr165Phe (EnsemblPlants:AT3G09960.1) - c.494A>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH02127225 | 168 | P>T | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.02) Somatic: No Accession: 3:g.3062491C>A Codon: CCT/ACT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062491C>A Locations: - p.Pro168Thr (EnsemblPlants:AT3G09960.1) - c.502C>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3062498_G_A | 170 | G>E | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.05) Somatic: No Accession: 3:g.3062498G>A Codon: GGA/GAA Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062498G>A Locations: - p.Gly170Glu (EnsemblPlants:AT3G09960.1) - c.509G>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH05800919 | 173 | D>E | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.44) Somatic: No Accession: 3:g.3062789T>A Codon: GAT/GAA Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062789T>A Locations: - p.Asp173Glu (EnsemblPlants:AT3G09960.1) - c.519T>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH13890562 | 179 | P>T | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 3:g.3062805C>A Codon: CCT/ACT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062805C>A Locations: - p.Pro179Thr (EnsemblPlants:AT3G09960.1) - c.535C>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3062836_T_C | 189 | M>T | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.02) Somatic: No Accession: 3:g.3062836T>C Codon: ATG/ACG Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062836T>C Locations: - p.Met189Thr (EnsemblPlants:AT3G09960.1) - c.566T>C (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH00314298 | 193 | H>L | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.02) Somatic: No Accession: 3:g.3062848A>T Codon: CAT/CTT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062848A>T Locations: - p.His193Leu (EnsemblPlants:AT3G09960.1) - c.578A>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH00314298 | 193 | H>R | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: 3:g.3062848A>G Codon: CAT/CGT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062848A>G Locations: - p.His193Arg (EnsemblPlants:AT3G09960.1) - c.578A>G (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH05800920 | 194 | K>E | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: 3:g.3062850A>G Codon: AAA/GAA Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062850A>G Locations: - p.Lys194Glu (EnsemblPlants:AT3G09960.1) - c.580A>G (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH05800921 | 194 | K>T | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 3:g.3062851A>C Codon: AAA/ACA Consequence type: missense Cytogenetic band: Genomic location: 3:g.3062851A>C Locations: - p.Lys194Thr (EnsemblPlants:AT3G09960.1) - c.581A>C (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH10574567 | 201 | E>K | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.12) Somatic: No Accession: 3:g.3063021G>A Codon: GAA/AAA Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063021G>A Locations: - p.Glu201Lys (EnsemblPlants:AT3G09960.1) - c.601G>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH10574568 | 203 | E>G | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.06) Somatic: No Accession: 3:g.3063028A>G Codon: GAG/GGG Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063028A>G Locations: - p.Glu203Gly (EnsemblPlants:AT3G09960.1) - c.608A>G (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH05800923 | 204 | E>D | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.57) Somatic: No Accession: 3:g.3063032A>T Codon: GAA/GAT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063032A>T Locations: - p.Glu204Asp (EnsemblPlants:AT3G09960.1) - c.612A>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH05800924 | 207 | T>K | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: 3:g.3063040C>A Codon: ACG/AAG Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063040C>A Locations: - p.Thr207Lys (EnsemblPlants:AT3G09960.1) - c.620C>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH10574569 | 213 | A>G | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.14) Somatic: No Accession: 3:g.3063058C>G Codon: GCC/GGC Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063058C>G Locations: - p.Ala213Gly (EnsemblPlants:AT3G09960.1) - c.638C>G (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH10574569 | 213 | A>V | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.04) Somatic: No Accession: 3:g.3063058C>T Codon: GCC/GTC Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063058C>T Locations: - p.Ala213Val (EnsemblPlants:AT3G09960.1) - c.638C>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3063070_G_A | 217 | G>D | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 3:g.3063070G>A Codon: GGT/GAT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063070G>A Locations: - p.Gly217Asp (EnsemblPlants:AT3G09960.1) - c.650G>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH05800927 | 221 | K>E | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.64) Somatic: No Accession: 3:g.3063081A>G Codon: AAG/GAG Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063081A>G Locations: - p.Lys221Glu (EnsemblPlants:AT3G09960.1) - c.661A>G (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH05800928 | 225 | E>K | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.65) Somatic: No Accession: 3:g.3063093G>A Codon: GAA/AAA Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063093G>A Locations: - p.Glu225Lys (EnsemblPlants:AT3G09960.1) - c.673G>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH10574570 | 246 | G>R | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 3:g.3063156G>C Codon: GGT/CGT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063156G>C Locations: - p.Gly246Arg (EnsemblPlants:AT3G09960.1) - c.736G>C (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH10574574 | 260 | K>R | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.31) Somatic: No Accession: 3:g.3063298A>G Codon: AAA/AGA Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063298A>G Locations: - p.Lys260Arg (EnsemblPlants:AT3G09960.1) - c.779A>G (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3063345_G_T | 276 | G>C | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 3:g.3063345G>T Codon: GGC/TGC Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063345G>T Locations: - p.Gly276Cys (EnsemblPlants:AT3G09960.1) - c.826G>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3063356_G_T | 279 | L>F | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.21) Somatic: No Accession: 3:g.3063356G>T Codon: TTG/TTT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063356G>T Locations: - p.Leu279Phe (EnsemblPlants:AT3G09960.1) - c.837G>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH05800937 | 282 | D>N | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 3:g.3063363G>A Codon: GAT/AAT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063363G>A Locations: - p.Asp282Asn (EnsemblPlants:AT3G09960.1) - c.844G>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
tmp_3_3063381_A_G | 288 | T>A | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.52) Somatic: No Accession: 3:g.3063381A>G Codon: ACC/GCC Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063381A>G Locations: - p.Thr288Ala (EnsemblPlants:AT3G09960.1) - c.862A>G (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH05800939 | 290 | T>K | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: 3:g.3063388C>A Codon: ACA/AAA Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063388C>A Locations: - p.Thr290Lys (EnsemblPlants:AT3G09960.1) - c.869C>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH05800940 | 291 | P>H | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 3:g.3063391C>A Codon: CCT/CAT Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063391C>A Locations: - p.Pro291His (EnsemblPlants:AT3G09960.1) - c.872C>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH00314301 | 306 | T>I | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.04) Somatic: No Accession: 3:g.3063436C>T Codon: ACC/ATC Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063436C>T Locations: - p.Thr306Ile (EnsemblPlants:AT3G09960.1) - c.917C>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH10574617 | 308 | N>K | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.68) Somatic: No Accession: 3:g.3063443T>A Codon: AAT/AAA Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063443T>A Locations: - p.Asn308Lys (EnsemblPlants:AT3G09960.1) - c.924T>A (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: | |||||||
ENSVATH05800941 | 310 | S>F | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: 3:g.3063448C>T Codon: TCC/TTC Consequence type: missense Cytogenetic band: Genomic location: 3:g.3063448C>T Locations: - p.Ser310Phe (EnsemblPlants:AT3G09960.1) - c.929C>T (EnsemblPlants:AT3G09960.1) Source type: large scale study Cross-references: |