Q8LBZ7 · SDHB1_ARATH

Function

function

Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

Note: Binds 1 [2Fe-2S] cluster.
[3Fe-4S] cluster (UniProtKB | Rhea| CHEBI:21137 )

Note: Binds 1 [3Fe-4S] cluster.
[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site102[2Fe-2S] cluster (UniProtKB | ChEBI)
Binding site107[2Fe-2S] cluster (UniProtKB | ChEBI)
Binding site122[2Fe-2S] cluster (UniProtKB | ChEBI)
Binding site194[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site197[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site200[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site204[3Fe-4S] cluster (UniProtKB | ChEBI)
Binding site209a ubiquinone (UniProtKB | ChEBI); ligand shared with SdhD subunit
Binding site251[3Fe-4S] cluster (UniProtKB | ChEBI)
Binding site257[3Fe-4S] cluster (UniProtKB | ChEBI)
Binding site261[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentmitochondrial inner membrane
Cellular Componentmitochondrion
Cellular Componentrespiratory chain complex II (succinate dehydrogenase)
Molecular Function2 iron, 2 sulfur cluster binding
Molecular Function3 iron, 4 sulfur cluster binding
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionelectron transfer activity
Molecular Functionsuccinate dehydrogenase (quinone) activity
Molecular Functionsuccinate dehydrogenase activity
Molecular Functionzinc ion binding
Biological Processmitochondrial electron transport, succinate to ubiquinone
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 1, mitochondrial
  • EC number
  • Alternative names
    • Iron-sulfur subunit of complex II (Ip)

Gene names

    • Name
      SDH2-1
    • ORF names
      K1G2.9
    • Ordered locus names
      At3g27380

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8LBZ7
  • Secondary accessions
    • Q9G3M0
    • Q9LTZ2

Proteomes

Organism-specific databases

Genome annotation databases

PTM/Processing

Features

Showing features for transit peptide, chain.

TypeIDPosition(s)Description
Transit peptide1-28Mitochondrion
ChainPRO_000024759529-279Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 1, mitochondrial

Proteomic databases

Expression

Tissue specificity

Ubiquitous. Preferentially expressed in flowers and inflorescences.

Developmental stage

Expressed in floral meristems and sex organ primordia at early stages of development. Later expressed in anthers, particularly in the tapetum, pollen mother cells, and microspores.

Gene expression databases

Interaction

Subunit

Component of complex II composed of eight subunits in plants: four classical SDH subunits SDH1, SDH2, SDH3 and SDH4 (a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.), as well as four subunits unknown in mitochondria from bacteria and heterotrophic eukaryotes.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain52-1412Fe-2S ferredoxin-type
Domain184-2144Fe-4S ferredoxin-type

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    279
  • Mass (Da)
    31,171
  • Last updated
    2006-07-25 v2
  • Checksum
    ADA885EC59A3EA36
MASGLIGRLVGTKPSKLATAARLIPARWTSTGAEAETKASSGGGRGSNLKTFQIYRWNPDNPGKPELQNYQIDLKDCGPMVLDALIKIKNEMDPSLTFRRSCREGICGSCAMNIDGCNGLACLTKIQDEASETTITPLPHMFVIKDLVVDMTNFYNQYKSIEPWLKRKTPASVPAKEILQSKKDRAKLDGMYECILCACCSTSCPSYWWNPESYLGPAALLHANRWISDSRDEYTKERLEAIDDEFKLYRCHTILNCARACPKGLNPGKQITHIKQLQR

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict20in Ref. 1; CAC19855 and 6; AAM63946
Sequence conflict26in Ref. 1; CAC19855 and 6; AAM63946
Sequence conflict200in Ref. 6; AAM63946

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ278910
EMBL· GenBank· DDBJ
CAC19855.1
EMBL· GenBank· DDBJ
mRNA
AB024028
EMBL· GenBank· DDBJ
BAA95713.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE77309.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE77310.1
EMBL· GenBank· DDBJ
Genomic DNA
AY035013
EMBL· GenBank· DDBJ
AAK59518.1
EMBL· GenBank· DDBJ
mRNA
AY063053
EMBL· GenBank· DDBJ
AAL34227.1
EMBL· GenBank· DDBJ
mRNA
AY924777
EMBL· GenBank· DDBJ
AAX23852.1
EMBL· GenBank· DDBJ
mRNA
AY086901
EMBL· GenBank· DDBJ
AAM63946.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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