Q8L8Y3 · PCEP1_ARATH

Function

function

Extracellular signaling peptide that represses, in a dose-dependent manner, primary root growth rate and lateral root elongation by inhibiting both cell division in meristems and cell growth in elongation zones. Prevents also slightly growth of above-ground parts (PubMed:18315543).
Regulates systemic nitrogen (N)-demand signaling. Mediates systemic up-regulation of genes involved in N uptake and assimilation pathways (e.g. NRT1.1, NRT2.1 and NRT3.1) (PubMed:25324386).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentapoplast
Cellular Componentextracellular space
Molecular Functionhormone activity
Biological Processcell surface receptor signaling pathway
Biological Processcellular response to ammonium ion
Biological Processcellular response to nitrogen starvation
Biological Processlateral root development
Biological Processnegative regulation of cell division
Biological Processnegative regulation of cell growth
Biological Processnitrate import
Biological Processnitrogen utilization
Biological Processphotoperiodism, flowering
Biological Processregulation of root development
Biological Processresponse to auxin
Biological Processresponse to nitrate starvation
Biological Processresponse to osmotic stress
Biological Processresponse to salt stress
Biological Processroot development

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Precursor of CEP1
  • Short names
    PCEP1
  • Cleaved into 1 chains

Gene names

    • Name
      CEP1
    • ORF names
      F16N3
    • Ordered locus names
      At1g47485

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8L8Y3
  • Secondary accessions
    • A0MEB7

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

C-terminally encoded peptide 1

Note: Accumulates in xylem sap under nitrogen (N)-starved conditions.

Keywords

PTM/Processing

Features

Showing features for signal, propeptide, peptide, modified residue.

TypeIDPosition(s)Description
Signal1-28
PropeptidePRO_000043996029-71
PeptidePRO_000043996172-86C-terminally encoded peptide 1
Modified residue75Hydroxyproline; partial
Modified residue78Hydroxyproline
Modified residue82Hydroxyproline; partial
PropeptidePRO_000043996287-91

Post-translational modification

The mature small signaling peptide is generated by proteolytic processing of the longer precursor.

Keywords

Proteomic databases

Expression

Tissue specificity

Mainly expressed in the lateral root primordia (PubMed:18315543).
Also present in the shoot apical meristem (SAM) (PubMed:18315543, PubMed:24179095).
Detected in the primary root apical meristem, at the root-hypocotyl junction, roots, leaves (in the small dentations at the leaf margin), siliques and flowers (PubMed:24179095).

Induction

Induced by auxin and nitrogen (N) (PubMed:24179095).
Induced in shoots in response to nitrogen and nitrate starvation (PubMed:24179096, PubMed:25324386).
Accumulates also under osmotic stress (e.g. mannitol and NaCl) (PubMed:24179096).

Developmental stage

In young seedlings, only observed in lateral root primordia, first in the core region at stage VI, in which cells of outer layer 2 undergo a periclinal division, creating a new internal layer (PubMed:18315543, PubMed:24179095).
Maximum levels are reached at the emergence stage, and steeply decrease after elongation of lateral roots, except for residual expression in the region of vascular connection. In two weeks old seedlings, also present in the shoot apical mersitem (SAM) (PubMed:18315543).
Accumulates during flower development and during lateral root development. In flowers, present in the gynoecium (PubMed:24179095).
Repressed upon floral induction (PubMed:14573523).

Gene expression databases

Interaction

Subunit

Interacts with the CEP receptors CEPR1 and CEPR2.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region69-91Disordered
Compositional bias74-91Polar residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    91
  • Mass (Da)
    10,080
  • Last updated
    2002-10-01 v1
  • Checksum
    0F9B56B9AEA2B559
MGMSNRSVSTSIFFLALVVLHGIQDTEERHLKTTSLEIEGIYKKTEAEHPSIVVTYTRRGVLQKEVIAHPTDFRPTNPGNSPGVGHSNGRH

Sequence caution

The sequence ABK28436.1 differs from that shown. Reason: Erroneous termination Extended C-terminus.

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias74-91Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB333778
EMBL· GenBank· DDBJ
BAG34615.1
EMBL· GenBank· DDBJ
mRNA
AC007519
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CP002684
EMBL· GenBank· DDBJ
AEE32172.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ446335
EMBL· GenBank· DDBJ
ABE65696.1
EMBL· GenBank· DDBJ
mRNA
DQ652886
EMBL· GenBank· DDBJ
ABK28436.1
EMBL· GenBank· DDBJ
mRNA Sequence problems.
AY088738
EMBL· GenBank· DDBJ
AAM67056.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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