Q8L716 · U2A2B_ARATH
- ProteinSplicing factor U2af large subunit B
- GeneU2AF65B
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids589 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Necessary for the splicing of pre-mRNA.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nuclear speck | |
Cellular Component | nucleus | |
Cellular Component | spliceosomal complex | |
Molecular Function | RNA binding | |
Biological Process | mRNA splicing, via spliceosome | |
Biological Process | response to abscisic acid |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameSplicing factor U2af large subunit B
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ8L716
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000352268 | 1-589 | Splicing factor U2af large subunit B | |||
Sequence: MMSYEGNGDGVAISTENHNENYISLESSPFHEDSKSRESHDLKKDSSKISEKDNENGRDKDGNKDRDREKDRDREKSRDRDREKSRDRDRDRERSKDRQRDRHHRDRHRDRSRERSEKRDDLDDDHHRRSRDRDRRRSRDRDREVRHRRRSRSRSRSRSERRSRSEHRHKSEHRSRSRSRSRSKSKRRSGFDMAPPDMLAATAVAAAGQVPSVPTTATIPGMFSNMFPMVPGQQLGALPVLPVQAMTQQATRHARRVYVGGLPPTANEQSVSTFFSQVMSAIGGNTAGPGDAVVNVYINHEKKFAFVEMRSVEEASNAMALDGIILEGVPVKVRRPTDYNPSLAATLGPSQPNPNLNLGAVGLSSGSTGGLEGPDRIFVGGLPYYFTEVQIRELLESFGPLRGFNLVKDRETGNSKGYAFCVYQDPSVTDIACAALNGIKMGDKTLTVRRAIQGAIQPKPEQEEVLLYAQQQIALQRLMFQPGGTPTKIVCLTQVVTADDLRDDEEYAEIMEDMRQEGGKFGNLVNVVIPRPNPDHDPTPGVGKVFLEYADVDGSSKARSGMNGRKFGGNQVVAVYYPEDKYAQGDYED |
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-195 | Disordered | ||||
Sequence: MMSYEGNGDGVAISTENHNENYISLESSPFHEDSKSRESHDLKKDSSKISEKDNENGRDKDGNKDRDREKDRDREKSRDRDREKSRDRDRDRERSKDRQRDRHHRDRHRDRSRERSEKRDDLDDDHHRRSRDRDRRRSRDRDREVRHRRRSRSRSRSRSERRSRSEHRHKSEHRSRSRSRSRSKSKRRSGFDMAP | ||||||
Compositional bias | 10-29 | Polar residues | ||||
Sequence: GVAISTENHNENYISLESSP | ||||||
Compositional bias | 30-100 | Basic and acidic residues | ||||
Sequence: FHEDSKSRESHDLKKDSSKISEKDNENGRDKDGNKDRDREKDRDREKSRDRDREKSRDRDRDRERSKDRQR | ||||||
Compositional bias | 110-141 | Basic and acidic residues | ||||
Sequence: DRSRERSEKRDDLDDDHHRRSRDRDRRRSRDR | ||||||
Compositional bias | 142-185 | Basic residues | ||||
Sequence: DREVRHRRRSRSRSRSRSERRSRSEHRHKSEHRSRSRSRSRSKS | ||||||
Domain | 255-338 | RRM 1 | ||||
Sequence: RRVYVGGLPPTANEQSVSTFFSQVMSAIGGNTAGPGDAVVNVYINHEKKFAFVEMRSVEEASNAMALDGIILEGVPVKVRRPTD | ||||||
Domain | 375-453 | RRM 2 | ||||
Sequence: DRIFVGGLPYYFTEVQIRELLESFGPLRGFNLVKDRETGNSKGYAFCVYQDPSVTDIACAALNGIKMGDKTLTVRRAIQ | ||||||
Domain | 494-580 | RRM 3 | ||||
Sequence: QVVTADDLRDDEEYAEIMEDMRQEGGKFGNLVNVVIPRPNPDHDPTPGVGKVFLEYADVDGSSKARSGMNGRKFGGNQVVAVYYPED |
Domain
N-terminal RS domain has a very strong bias in favor of D over S.
Sequence similarities
Belongs to the splicing factor SR family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length589
- Mass (Da)66,316
- Last updated2008-10-14 v2
- ChecksumC94E70DBA2621601
Sequence caution
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 10-29 | Polar residues | ||||
Sequence: GVAISTENHNENYISLESSP | ||||||
Compositional bias | 30-100 | Basic and acidic residues | ||||
Sequence: FHEDSKSRESHDLKKDSSKISEKDNENGRDKDGNKDRDREKDRDREKSRDRDREKSRDRDRDRERSKDRQR | ||||||
Compositional bias | 110-141 | Basic and acidic residues | ||||
Sequence: DRSRERSEKRDDLDDDHHRRSRDRDRRRSRDR | ||||||
Compositional bias | 142-185 | Basic residues | ||||
Sequence: DREVRHRRRSRSRSRSRSERRSRSEHRHKSEHRSRSRSRSRSKS | ||||||
Sequence conflict | 255 | in Ref. 3; AAM98156 | ||||
Sequence: R → P |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC018908 EMBL· GenBank· DDBJ | AAG51641.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002684 EMBL· GenBank· DDBJ | AEE33746.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY140014 EMBL· GenBank· DDBJ | AAM98156.1 EMBL· GenBank· DDBJ | mRNA |