Q8L500 · APRR9_ARATH

Function

function

Transcriptional repressor of CCA1 and LHY, and positive regulator of LWD1 and LWD2 expression. Controls photoperiodic flowering response and temperature compensation. Involved in the positive and negative feedback loops of the circadian clock. Expression of several members of the ARR-like family is controlled by circadian rhythm. Regulated at the transcriptional level by a corepressor complex consisting of ELF4, ELF3, and LUX. APRR9, APRR7, and APRR5 coordinately act on the upstream region of the target genes to repress their expression from noon until midnight. The particular coordinated sequential expression of APRR9, APRR7, APRR5, APRR3 and APPR1 result to circadian waves that may be at the basis of the endogenous circadian clock.

Miscellaneous

Regulated at the level of mRNA maturation and alternative splicing by SKIP (PubMed:22942380) and PRMT5 (PubMed:20962777).
The expression of APRR9, APRR7, and APRR5 requires the presence of LWD1 and/or LWD2, indicating the existence of a positive feedback loop within the circadian clock (PubMed:21357491).

Caution

Lacks the phospho-accepting Asp (here Glu-89), present in the receiver domain, which is one of the conserved features of two-component response regulators (ARRs) family.

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA binding
Biological Processcircadian rhythm
Biological Processcytokinin-activated signaling pathway
Biological Processnegative regulation of DNA-templated transcription
Biological Processphosphorelay signal transduction system
Biological Processred or far-red light signaling pathway
Biological Processregulation of DNA-templated transcription

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Two-component response regulator-like APRR9
  • Alternative names
    • Pseudo-response regulator 9

Gene names

    • Name
      APRR9
    • ORF names
      F19D11.7
    • Ordered locus names
      At2g46790

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8L500
  • Secondary accessions
    • O81035
    • Q9LKL1

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000814411-468Two-component response regulator-like APRR9

Post-translational modification

Phosphorylated. Phosphorylation varies throughout the diurnal cycle.

Keywords

Proteomic databases

Expression

Induction

Up-regulated by heat-shock.

Gene expression databases

Interaction

Binary interactions

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain38-156Response regulatory
Region168-203Disordered
Region302-416Disordered
Compositional bias313-327Basic and acidic residues
Compositional bias328-367Polar residues
Compositional bias381-398Polar residues
Compositional bias399-416Basic and acidic residues
Domain417-459CCT
Region442-468Disordered

Sequence similarities

Belongs to the ARR-like family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete

This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.

Q8L500-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    468
  • Mass (Da)
    52,565
  • Last updated
    2004-09-27 v2
  • Checksum
    19D6C9571CA77A40
MGEIVVLSSDDGMETIKNRVKSSEVVQWEKYLPKTVLRVLLVESDYSTRQIITALLRKCCYKVVAVSDGLAAWEVLKEKSHNIDLILTELDLPSISGFALLALVMEHEACKNIPVIMMSSQDSIKMVLKCMLRGAADYLIKPMRKNELKNLWQHVWRRLTLRDDPTAHAQSLPASQHNLEDTDETCEDSRYHSDQGSGAQAINYNGHNKLMENGKSVDERDEFKETFDVTMDLIGGIDKRPDSIYKDKSRDECVGPELGLSLKRSCSVSFENQDESKHQKLSLSDASAFSRFEESKSAEKAVVALEESTSGEPKTPTESHEKLRKVTSDQGSATTSSNQENIGSSSVSFRNQVLQSTVTNQKQDSPIPVESNREKAASKEVEAGSQSTNEGIAGQSSSTEKPKEEESAKQRWSRSQREAALMKFRLKRKDRCFDKKVRYQSRKKLAEQRPRVKGQFVRTVNSDASTKS

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1P8B286A0A1P8B286_ARATHPRR9444
A0A1P8B243A0A1P8B243_ARATHPRR9311
F4IJA1F4IJA1_ARATHPRR9351

Sequence caution

The sequence AAM20527.1 differs from that shown. Reason: Frameshift
The sequence AAM91256.1 differs from that shown. Reason: Frameshift

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias313-327Basic and acidic residues
Compositional bias328-367Polar residues
Compositional bias381-398Polar residues
Compositional bias399-416Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB046953
EMBL· GenBank· DDBJ
BAB13741.1
EMBL· GenBank· DDBJ
mRNA
AF272040
EMBL· GenBank· DDBJ
AAF86253.1
EMBL· GenBank· DDBJ
mRNA
AC005310
EMBL· GenBank· DDBJ
AAC33497.2
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC10754.1
EMBL· GenBank· DDBJ
Genomic DNA
AY099676
EMBL· GenBank· DDBJ
AAM20527.1
EMBL· GenBank· DDBJ
mRNA Frameshift
AY128856
EMBL· GenBank· DDBJ
AAM91256.1
EMBL· GenBank· DDBJ
mRNA Frameshift

Genome annotation databases

Similar Proteins

Disclaimer

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