Q8K9H5 · PNP_BUCAP
- ProteinPolyribonucleotide nucleotidyltransferase
- Genepnp
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids707 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
Catalytic activity
- RNA(n+1) + phosphate = RNA(n) + a ribonucleoside 5'-diphosphate
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 486 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 492 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 3'-5'-RNA exonuclease activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | polyribonucleotide nucleotidyltransferase activity | |
Molecular Function | RNA binding | |
Biological Process | mRNA catabolic process | |
Biological Process | RNA processing |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePolyribonucleotide nucleotidyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Erwiniaceae > Buchnera
Accessions
- Primary accessionQ8K9H5
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000197911 | 1-707 | Polyribonucleotide nucleotidyltransferase | ||
Interaction
Subunit
Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 553-612 | KH | |||
Domain | 622-690 | S1 motif | |||
Sequence similarities
Belongs to the polyribonucleotide nucleotidyltransferase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length707
- Mass (Da)78,389
- Last updated2002-10-01 v1
- Checksum9D5367E96E91520A
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE013218 EMBL· GenBank· DDBJ | AAM67914.1 EMBL· GenBank· DDBJ | Genomic DNA |