Q8K9H5 · PNP_BUCAP

Function

function

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site.

170750100150200250300350400450500550600650700
TypeIDPosition(s)Description
Binding site486Mg2+ (UniProtKB | ChEBI)
Binding site492Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function3'-5'-RNA exonuclease activity
Molecular Functionmagnesium ion binding
Molecular Functionpolyribonucleotide nucleotidyltransferase activity
Molecular FunctionRNA binding
Biological ProcessmRNA catabolic process
Biological ProcessRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyribonucleotide nucleotidyltransferase
  • EC number
  • Alternative names
    • Polynucleotide phosphorylase
      (PNPase
      )

Gene names

    • Name
      pnp
    • Ordered locus names
      BUsg_361

Organism names

Accessions

  • Primary accession
    Q8K9H5

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001979111-707Polyribonucleotide nucleotidyltransferase

Interaction

Subunit

Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain553-612KH
Domain622-690S1 motif

Sequence similarities

Belongs to the polyribonucleotide nucleotidyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    707
  • Mass (Da)
    78,389
  • Last updated
    2002-10-01 v1
  • Checksum
    9D5367E96E91520A
MLNPIVRKFQYGQHTITLETGIMARQATAAVMASMDDTAVFVTVVGEKTTNSSQKFFPLTVNYQERTYAVGRIPGGFFRREGRPSENEILTARLIDRPIRPLFPKGFCNEIQIIATVVSVNPQINPDIISIIGASAALSLSGIPFYGPIGAARVGFVNNQYVLNPTIDDMKSSFLDLVVSGTQNAVLMVEAESKVLSEDKILGAIMFGHQQQQVVINNIRSLSNEASKLPWIISYPEINTELELKITKLAEKDISNAYLIFNKQERYEKLNFLKEEIIKLFFSENSNIDISEIEDIFEKIEKNIVRKRILNNENRIDGREKDMIRALDIRTGVLPRTHGSSLFTRGETQSLVSVTLGTSRDAQNLDELLGDKTDNFLFHYNFPPYSVGEIGIVGSPKRREIGHGRLAKRSLLAVMPKLDDFPYTIRIVSEITESNGSSSMASVCGASLALMDAGVPIKSAVAGISMGLVKEGDKYVLLSDILGDEDHLGDMDFKVSGTEEGITALQMDIKIEGITNEIMRIALNKAKSARLHILNVMKQALSKPRNEISEFAPRIHKIKINPEKIKDVIGKGGSVIRMLTEETGTIIEIEDDGTIKISATIGEKAKNAIRRIEEITAEIEVGRIYSGKVTRIVDFGAFISIGIGKEGLVHISQISNKRVEKVSDHLTVDQIISVKVLEIDRQGRLRLSIKEVENSIISNKSINNIYI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE013218
EMBL· GenBank· DDBJ
AAM67914.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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